Publications

2019年度

Takayuki Chikata, Wayne Paes, Tomohiro Akahoshi, Thomas Partridge, Hayato Murakoshi, Hiroyuki Gatanaga, Nicola Ternette, Shinichi Oka, Persephone Borrow, and Masafumi Takiguchi, Identification of immunodominant HIV-1 epitopes presented by HLA-C*12:02, a protective allele, using an immunopeptidomics approach, J. Virol, 93(17), e00634-19,2019(国際連携分野(滝口研))

G Barabona, M Mahiti, S Masoud, P Mbelele, A Shaban Mgunya, L Minja, B Sunguya, U Shigemi, M Matsuda, A Hachiya, Y Iwatani, E Lyamuya, T Ueno (2019) Pre-treatment and acquired HIV drug resistance in Dar es Salaam, Tanzania in the era of tenofovir and routine viral load monitoring. J Antimicrob Chemother  https://doi.org/10.1093/jac/dkz272(感染免疫学分野)

Ueno M, Nogawa M, Siddiqui R, Watashi K, Wakita T, Kato N, Ikeda M, Okimura T, Isaka S, Oda T, Ariumi Y. Acidic polysaccharides isolated from marine algae inhibit the early step of viral infection. Int. J. Biol. Macromol. 124:282-290, 2019.(レトロエレメント学分野)

Smita Kulkarni, Alexandra Lied, Viraj Kulkarni, Marijana Rucevic, Maureen P. Martin, Victoria Walker-Sperling, Stephen K. Anderson, Rodger Ewy, Sukhvinder Singh, Hoang Nguyen, Paul J. McLaren, Mathias Viard, Vivek Naranbhai, Chengcheng Zou, Zhansong Lin, Hiroyuki Gatanaga, Shinichi Oka, Masafumi Takiguchi, Chloe L. Thio, Joseph Margolick, Gregory D. Kirk, James J. Goedert, W. Keith Hoots, Steven G. Deeks, David W. Haas, Nelson Michael, Bruce Walker, Sylvie Le Gall, Fatema Z. Chowdhury, Xu G. Yu and Mary Carrington, CCR5AS lncRNA variation differentially regulates CCR5, influencing HIV disease outcome, Nat Immunol. 20:824-834, 2019(国際連携分野(滝口研))

Nozomi Kuse, Xiaoming Sun, Tomohiro Akahoshi, Anna Lissina, Takuya Yamamoto, Victor Appay, and Masafumi Takiguchi, Priming of HIV-1-specific CD8+ T cells with strong functional properties from naive T cells, EBioMedicine 42:109-119, 2019(国際連携分野(滝口研))

Chengcheng Zou*, Hayato Murakoshi*, Nozomi Kuse, Tomohiro Akahoshi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, Tomas Hanke, and Masafumi Takiguchi (*Equal contribution), Effective suppression of HIV-1 replication by CTLs specific for Pol epitopes in conserved mosaic vaccine immunogens, J. Virol. 93:e02142-18, 2019(国際連携分野(滝口研))

Chengcheng Zou*, Hayato Murakoshi*, Nozomi Kuse, Tomohiro Akahoshi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, Tomas Hanke, and Masafumi Takiguchi (*Equal contribution), Effective suppression of HIV-1 replication by CTLs specific for Pol epitopes in conserved mosaic vaccine immunogens, J. Virol. 93:e02142-18, 2019(国際連携分野(滝口研))

Iwase SC, Miyazato P, Katsuya H, Islam S, Tan B, Ito J, Matsuo M, Takeuchi H, Ishida T, Matsuda K, Maeda K, and Satou Y. HIV-1 DNA-capture-seq is a useful tool for the comprehensive characterization of HIV-1 provirus. Sci Rep, 9(1):12326, 2019(ゲノミクス・トランスクリプトミクス学分野)

2018年度

Katsuya H, Cook LBM, Rowan AG, Satou Y, Taylor G, Bangham CRM. Phosphatidylinositol 3-kinase-δ (PI3K-δ) is a potential therapeutic target in adult T-cell leukemia-lymphoma. Biomark Res, 6:24, 2018(ゲノミクス・トランスクリプトミクス学分野)

Miura M, Miyazato P, Satou Y, Tanaka Y, Bangham CRM. Spontaneous HTLV-1 transcription is accompanied by distinct epigenetic changes in the 5′ and 3′ long terminal repeats. Wellcome Open Research, 3:105, 2018(ゲノミクス・トランスクリプトミクス学分野)

F Mwimanzi, M Toyoda, M Mahiti, J Mann, J Martin, D Bangsberg, M Brockman, P Goulder, F Kirchhoff, Z Brumme, T Ndung’u, T Ueno (2018) Resistance of major histocompatibility complex class B (MHC-B) to Nef-mediated downregulation relative to that of MHC-A is conserved among primate lentiviruses and influences antiviral T cell responses in HIV-1-infected individuals. J Virol 92: e01409-17 https://doi.org/10.1128/JVI.01409-17(感染免疫学分野)

Siddiqui R, Suzu S, Ueno M, Nasser H, Koba R, Bhuyan F, Noyori O, Yasuda-Inoue M, Hishiki T, Sukegawa S, Miyagi E, Strebel K, Matsushita S, Shimotohno K, Ariumi Y. Apolipoprotein E is an HIV-1-inducible inhibitor of viral production and infectivity in macrophages. PLoS Pathog. 14:e1007372, 2018.(レトロエレメント学分野)

Kawano K, Doucet A, Ueno M, Kuroki M, Turelli P, An W, Cristofari G, Trono D, Ariumi Y. HIV-1 Vpr and p21Waf1 restrict the LINE-1 mobility. Nucleic Acid Res. 46:8454-8470, 2018 (レトロエレメント学分野)

Ariumi Y, Kawano K, Yasuda-Inoue M, Fukuda H, Siddiqui R, Turelli P, Tateishi S. DNA repair protein Rad18 restricts LINE-1 mobility. Sci Rep. 8:15894. 2018.(レトロエレメント学分野)

Hayato Murakoshi, Madoka Koyanagi, Tomohiro Akahoshi, Takayuki Chikata, Nozomi Kuse, Hiroyuki Gatanaga, Sarah L Rowland-Jones, Shinichi Oka, and Masafumi Takiguchi, Impact of a Single HLA-A*24:02-associated Escape Mutation on the Detrimental Effect of HLA-B*35:01 in HIV-1 Control, EBioMedicine 36:103-112, 2018(国際連携分野(滝口研))

Takayuki Chikata*, Giang Van Tran*, Hayato Murakoshi, Tomohiro Akahoshi, Ying Qi, Vivek Naranbhai, Nozomi Kuse, Yoshiko Tamura, Madoka Koyanagi, Sachiko Sakai, Dung Hoai Nguyen, Dung Thi Nguyen, Ha Thu Nguyen, Trung Vu Nguyen, Shinichi Oka, Maureen P. Martin, Mary Carrington, Keiko Sakai, Kinh Van Nguyen, and Masafumi Takiguchi (*Equal contribution), HLA class I-mediated HIV-1 control in Vietnamese infected with HIV-1 subtype A/E, J. Virol. 92:e01749-17, 2018(国際連携分野(滝口研))

2017年度

Satou Y#*, Katsuya H#, Fukuda A, Misawa N, Miyazato P, Islam MS, Fassati A, Melamed A, Bangham CRM, Koyanagi Y, Sato K. Dynamics and mechanisms of clonal expansion of HIV-1-infected cells in a humanized mouse model. (#equal contribution, *corresponding author) Sci Rep, 7: 6913, 2017 (ゲノミクス・トランスクリプトミクス学分野)

Takayuki Chikata*, Hayato Murakoshi*, Madoka Koyanagi, Kazutaka Honda, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi (*Equal contribution), Control of HIV-1 by an HLA-B*52:01-C*12:02 protective haplotype, J. Infect. Dis. 216:1415-1424, 2017 (国際連携分野(滝口研))

Hayato Murakoshi*, Madoka Koyanagi*, Takayuki Chikata, Mohammad Arif Rahman, Nozomi Kuse, Keiko Sakai, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi (*Equal contribution), Accumulation of Pol mutations selected by HLA-B*52:01-C*12:02 protective haplotype-restricted CTLs causes low plasma viral load due to low viral fitness of mutant viruses, J. Virol. 91:e02082-16, 2017 (国際連携分野(滝口研))

2016年度

Miyazato P, Katsuya H, Fukuda A, Uchiyama Y, Matsuo M, Tokunaga M, Hino S, Nakao M, and Satou Y*. Application of targeted enrichment to next-generation sequencing of retroviruses integrated into the host human genome. Sci Rep, 6:28324, 2016(ゲノミクス・トランスクリプトミクス学分野)

Satou Y*, Miyazato P, Ishihara K, Yaguchi H, Melamed A, Miura M, Fukuda A, Nosaka K, Watanabe T, Rowan A, Nakao M, and Bangham CRM*. The retrovirus HTLV-1 inserts an ectopic CTCF-binding site into the human genome. PNAS 113: 3054-59, 2016(ゲノミクス・トランスクリプトミクス学分野)

Zhansong Lin, Kimiko Kuroki, Nozomi Kuse, Xiaoming Sun, Tomohiro Akahoshi, Ying Qi, Takayuki Chikata, Takuya Naruto, Madoka Koyanagi, Hayato Murakoshi, Hiroyuki Gatanaga, Shinichi Oka, Mary Carrington, Katsumi Maenaka, Masafumi Takiguchi, HIV-1 control by NK cells via reduced interaction between KIR2DL2 and HLA-C*12:02/C*14:03, Cell Reports 17:2210-2220, 2016(国際連携分野(滝口研))

Xiaoming Sun, Yi Shi, Tomohiro Akahoshi, Mamoru Fujiwara, Hiroyuki Gatanaga, Christian Schonbach, Nozomi Kuse, Victor Appay, George F. Gao, Shinichi Oka, and Masafumi Takiguchi, Effects of a single escape mutation on T cell and HIV-1 co-adaptation, Cell Reports, 15:2279-2291, 2016(国際連携分野(滝口研))

Giang Van Tran*, Takayuki Chikata*, Jonathan M. Carson, Hayato Murakoshi, Dung Hoai Nguyen, Yoshiko Tamura, Tomohiro Akahoshi, Nozomi Kuse, Keiko Sakai, Sachiko Sakai, Kyle Cobarrubias, Shinichi Oka, Zabrina L. Brumme, Kinh Van Nguyen, and Masafumi Takiguchi (*Equal contribution), A strong association of HLA-associated Pol and Gag mutations with clinical parameters in HIV-1 subtype A/E infection, AIDS 30:681-689, 2016(国際連携分野(滝口研))

2015年度

Nozomi Kuse*, Mohammad Arif Rahman*, Hayato Murakoshi*, Giang Van Tran, Takayuki Chikata, Madoka Koyanagi, Kinh Van Nguyen, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi, Different Effects of Nonnucleoside Reverse Transcriptase Inhibitor Resistance Mutations on Cytotoxic T Lymphocyte Recognition between HIV-1 Subtype B and Subtype A/E Infections (*Equal contribution). J. Virol. 89:7363-7372, 2015(国際連携分野(滝口研))

Giang Van Tran*, Takayuki Chikata*, Jonathan M. Carson, Hayato Murakoshi, Dung Hoai Nguyen, Yoshiko Tamura, Tomohiro Akahoshi, Nozomi Kuse, Keiko Sakai, Sachiko Sakai, Kyle Cobarrubias, Shinichi Oka, Zabrina L. Brumme, Kinh Van Nguyen, and Masafumi Takiguchi (*Equal contribution), A strong association of HLA-associated Pol and Gag mutations with clinical parameters in HIV-1 subtype A/E infection, AIDS 30:681-689, 2016(国際連携分野(滝口研))

熊本大学キャンパス
生命化学研究部・教育部
IRCMS
IRCMS
ヒトレトロウイルス学共同研究センター 熊本キャンパス

Copyright @ 2019 Joint Research Center for Human Retrovirus Infection, Kumamoto University