大学院生業績
2004-2013

川島　夕佳 （大学院博士課程2007年度修了）

■論文発表
2013 Yuichi Yagita*, Nozomi Kuse*, Kimiko Kuroki*, Hiroyuki Gatanaga, Jonathan M. Carlson, Takayuki Chikata, Zabrina L. Brumme, Hayato Murakoshi, Tomohiro Akahoshi, Nico Pfeifer, Simon Mallal, Mina John, Toyoyuki Ose, Haruki Matsubara, Ryo Kanda, Yuko Fukunaga, Kazutaka Honda, Yuka Kawashima, Yasuo Ariumi, Shinichi Oka, Katsumi Maenaka, and Masafumi Takiguchi (*Equal contribution), Distinct HIV-1 Escape Patterns Selected by Cytotoxic T Cells with Identical Epitope Specificity, J. Virol. 87:2253-63, 2013
2011 Takuya Naruto, Hayato Murakoshi, Takayuki Chikata, Madoka Koyanagi, Yuka Kawashima, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi, Selection of HLA-B57-associated Gag A146P mutant by HLA-B*48:01-resticted Gag140-147-specific CTLs in chronically HIV-1-infected Japanese. Microbes and Infection 13: 766-770, 2011
2010 Yuka Kawashima*, Nozomi Kuse*, Hiroyuki Gatanaga*, Takuya Naruto, Mamoru Fujiwara, Sachi Dohki, Tomohiro Akahoshi, Katsumi Maenaka, Philip Goulder, Shinichi Oka, and Masafumi Takiguchi, Long-term control of HIV-1 in hemophiliacs carrying slow-progressing allele HLA-B*5101. J. Virol. 84:7151-7160, 2010 (* equal contribution)
Hirokazu Koizumi*, Masao Hashimoto*, Mamoru Fujiwara, Hayato Murakoshi, Takayuki Chikata, Mohamed Ali Borghan, Atsuko Hachiya, Yuka Kawashima, Hiroshi Takata, Takamasa Ueno, Shinichi Oka, and Masafumi Takiguchi, Different in vivo effects of HIV-1 immunodominant epitope-specific CTLs on selection of escape mutant viruses. J. Virol. 84: 5508-5519, 2010 (* equal contribution)
2009  Yuka Kawashima, Katja Pfafferott, John Frater, Philippa Matthews, Rebecca Payne, Marylyn Addo, Hiroyuki Gatanaga, Mamoru Fujiwara, Atsuko Hachiya, Hirokazu Koizumi, Nozomi Kuse, Shinichi Oka, Anna Duda, Andrew Prendergast, Hayley Crawford, Alasdair Leslie, Zabrina Brumme, Chanson Brumme, Todd Allen, Christian Brander, Richard Kaslow, James Tang, Eric Hunter, Susan Allen, Joseph Mulenga, Songee Branch, Tim Roach, Mina John, Simon Mallal, Anthony Ogwu, Roger Shapiro, Julia G. Prado, Sarah Fidler, Jonathan Weber, Oliver G. Pybus, Paul Klenerman, Thumbi Ndung’u, Rodney Phillips, David Heckerman, P. Richard Harrigan, Bruce D. Walker, Masafumi Takiguchi*, and Philip Goulder* (*equally contribution) Adaptation of HIV-1 to Human Leukocyte Antigen class I . Nature 458: 641-645, 2009
Hayato Murakoshi, Mitsutaka Kitano, Tomohiro Akahoshi, Yuka Kawashima, Sachi Dohki, Shinichi Oka and Masafumi Takiguchi, Identification and characterization of 2 HIV-1 Gag immunodominant epitopes restricted by Asian HLA allele HLA-B*4801, Human Immunol. 70: 170-174, 2009
2008 Mitsutaka Kitano, Naoki Kobayashi, Yuka Kawashima, Tomohiro Akahoshi, Kiyoshi Nokihara, Shinichi Oka and Masafumi Takighuchi, Identification and characterization of HLA-B*5401-restricted HIV-1-Nef and Pol-specific CTL epitopes, Microbe and Infection,10:764-772, 2008
Yuka Kawashima, Manami Satoh, Shinichi Oka, Takuma Shirasaka, and Masafumi Takiguchi, Different immunodominance of HIV-1-specific CTL epitopes among 3 subtypes of HLA-A*26 associated with slow progression to AIDS, Biochem. Biophys. Res. Commun. 366;612-616, 2008
Mamoru Fujiwara, Junko Tanuma, Hirokazu Koizumi, Yuka Kawashima, Kazutaka Honda, Saori Mastuoka-Aizawa, Sachi Dohki, Shinichi Oka and Masafumi Takiguchi, Different Ability of Escape Mutant-Specific Cytotoxic T Cells to Suppress Replication of Escape Mutant and Wild-type HIV-1 in New Hosts, J. Virol.,,82: 138-147, 2008
2005 Yuka Kawashima, Manami Satoh, Shinichi Oka, and Masafumi Takiguchi, Identification and characterization of HIV-1 epitopes presented by HLA-A*2603: Comparison between HIV-1 epitopes presented by A*2601 and A*2603, Human Immunol. 66: 1155-1166. 2005

■学会発表
2007 Yuka Kawashima, Mamoru Fujiwara and Masafumi Takiguchi; Long-term Control of HIV-1 by HIV-1-Specific CTLs and Appearance of Lower Fitness Virus in HLA-B*51+ Long term non-progressors, 第37回日本免疫学会学術集会(東京) 11月20日-22日, 2007
Yuka Kawashima, Mamoru Fujiwara, Hirohisa Gatanaga, Atsuko Hachiya, Mitsutaka Kitano, Shinichi Oka and Masafumi Takiguchi, Control of HIV-1 replication by strong immune pressure via HIV-1-specific cytotoxic T lymphocytes and appearance of lower fitness virus in long-term non-progressing hemophiliacs, Keystone Symposia HIV Vaccines(Whistler, Canada) March 25-30, 2007
2006 Y. Kawashima, M. Fujiwara, A. Hachiya, M. Kitano, S. Oka and M. Takiguchi, Role of two immunodominant Pol epitopes presented by HLA-B*51 in slow progression to AIDS, 7th AIDS Seminar in Kumamoto. (Kumamoto, Japan) September 21-22, 2006.  
川島夕佳、藤原守、蜂谷敦子、北野光崇、岡慎一、滝口雅文(2006) エイズ発症遅延HIV-1感染者で高頻度に認められるHLA-B*5101拘束性Pol特異的CTLの機能的解析　第５４回日本ウイルス学会学術集会（名古屋）11月19日〜21日
2005
川島夕佳、藤原守、佐藤愛美、岡慎一、滝口雅文 (2005) HLA-B*5101を持つ長期未発症者におけるHIV-1 Pol特異的CTLの役割 第19回日本エイズ学会学術集会(熊本)12月1日〜3日
川島夕佳、藤原守、佐藤愛美、岡慎一、滝口雅文 (2005) HLA-B*5101拘束性HIV-1 Pol特異的CTLのエイズ発症遅延における役割 第53回日本ウイルス学会学術集会(横浜)11月20日〜22日
Yuka Kawashima, Mamoru Fujiwara, Manami Satoh, Shinichi Oka and Masafumi Takiguchi, ANALYSIS OF TWO IMMUNODOMINANT POL EPITOPES PRESENTED BY HLA-A*51 ASSOCIATED WITH SLOW PROGRESSION TO AIDS: SPECULATION OF MECHANISMS FOR SUPRESSION OF VIRAL REPLICATION IN HLA-B*5101-POSITIVE LTNP, AIDS VACCINE 2005 INTERNATIONAL CONFERENCE (Montreal, Quebec, Canada) September 6 to 9, 2005→発表の様子はこちらから
Yuka Kawashima, Manami Satoh, Shinichi Oka, Masafumi Takiguchi, Identification of HIV-1-specific CTL epitopes presented by HLA-A*2603, Seventh International Congress on AIDS in Asia and the Pacific (Kobe, Japan) July 1-5, 2005
→発表の様子はこちらから
2004 優秀論文　川島夕佳、佐藤愛美、岡慎一、滝口雅文 (2004) HLA-A＊2603 に提示されるHIV-1 T 細胞エピトープ同定 第18回日本エイズ学会学術集会(静岡) 2004年12月9日〜11日
川島夕佳、佐藤愛美、岡慎一、滝口雅文 (2004)　HLA-A＊2603 に提示されるHIV-1 T 細胞エピトープ同定
第7回白馬シンポジウム2003　（札幌） 平成16年10月15日〜10月16日
Yuka Kawashima, Manami Satoh, Shinichi Oka, Masafumi Takiguchi. Identification of HIV-1-specific CD8+ T cell epitopes presented by HLA-A*2603, 5th AIDS Seminar in Kumamoto. (Kumamoto, Japan) September 9-10, 2004. 

■総説
2007
 川島夕佳、滝口雅文: HIVの観点から　分子細胞治療　6（2）　142-146, 2007


   
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