8th AIDS Seminar in KUMAMOTO
   第8回熊本エイズセミナープログラム

■ 14 September

Session I  Antiretroviral drugs


Yasuhiro Koh (Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan)
Potent inhibition of HIV-1 replication by novel non-peptidyl small molecule inhibitors of protease dimerization


Hirokazu Tamamura (Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo, Japan)
Development of anti-HIV agents based on chemokine receptor CXCR4 antagonists


Wataru Sugiura (National Institute of Infectious Diseases, Tokyo, Japan)
Genetic and structural interferences between protease inhibitor resistant mutations and Gag polymorphisms---their consequence in drug resistance selection and acquisition---


Ladislau C. Kovari (Wayne State University School of Medicne, Detroit, USA)
Structure-function studies of HIV-1 protease drug resistance

Session II  Immune responses and Vacccine I

Junji Shibata (Center for AIDS Research, Kumamoto University, Kumamoto, Japan)
The single mutation in V2 domain affects quaternary structure of trimer gp120 and dramatically increases the sensitivity of primary human immunodeficiency virus type 1 isolates to neutralizing antibodies


Takamasa Ueno (Center for AIDS Research, Kumamoto University, Kumamoto, Japan)
CTL-mediated selective pressure influences dynamic evolution and pathogenic functions of HIV-1 Nef


Marcus Altfeld (Harvard Medical School, Boston, USA)
HIV-1-specific CD8+ T cell responses in Acute HIV-1 Infection
     
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