PUBLICATIONS

業績

  • Aritsu, Y., Kitabatake, M., Kurose, A., Hamana, H., Nakama, T., Yamada, K., Furukawa, R., Ouji-Sageshima, N., Hara, A., Yasuike, K., Itami, S., Li, H., Udaka, K., Kishi, H., Ueno, T., Nakagawa, S., Ito, T., Kawashita, N., Kitamatsu, M., Motozono, C*. N-terminal pyroglutamylation of an HLA-A24-restricted immunodominant epitope enhances SARS-CoV-2-specific T cell responses, Frontiers in Immunology, In press, 2026.
  • Nakama, T#., Wall, A#., Dolton G#., Tan, LR., Thomas, H., Hamana, H., Aritsu, Y., Tan, TS., Toyoda, M., Goto, Y., Li, H., Kitamatsu, K., Udaka, K., Miyashita, Y., Oshiumi, H., Nakamura, K., Nagasaki, Y., Minami, R., Nakata, .H, Rizkallah, PJ., Kishi, H., Ueno, T., Sewell, AK*., Motozono, C*. Position-5-Driven Reorientation of the Immunodominant HLA-A*24:02 SARS-CoV-2 Epitope Underlies Universal T-cell Escape. JCI Insight, In press, 2026
  • Goto, Y#., Dolton, G#., Thomas, H., Morin, T., Tajima, Y., Imamura, K, Sakata, S., Oka, K., Hayashi, A., Takahashi, M., Ueno, T., Sakagami, T., Tomita, Y*., Sewell, AK*, and Motozono, C*. A probiotic bacterium modulates antitumor γδ T-cell responses in lung cancer. Frontiers in Immunology, In press, 2026.
  • Goto, Y., Ahn, YM., Toyoda, M., Hamana, H., Jin, Y., Aritsu, Y., Nakama, T., Tajima, Y., Maddumage, JC., Li, H., Kitamatsu, M., Kishi, H., Yonekawa, A., Jayasinghe, D., Shimono, N., Nagasaki, Y., Minami, R., Toya, T., Sekiya, N., Tomita, Y., Chatzileontiadou, DSM., Nakata, H., Nakagawa, S., Sakagami, T., Ueno, T., Gras, S*., Motozono, C*. Molecular basis of potent antiviral HLA-C-restricted CD8+ T cell response to an immunodominant SARS-CoV-2 nucleocapsid epitope. Nature Communications, 16(1):8062, 2025.
  • Motozono, C*., Toyoda, M., Tan, TS., Hamana, H., Aritsu, Y., Miyashita, Y., Oshiumi, H., Nakamura, K., Okada, S., Udaka, K., Kitamatsu, M., Kishi, H., Ueno, T*. The SARS-CoV-2 Omicron BA.1 spike G446S mutation potentiates antiviral T cell recognition. Nature Communications 13(1):5440, 2022. *Corresponding equally
  • Shibata, K, Motozono, C., Nagae M., Shimizu, T., Ishikawa, E., Motooka, D., Okuzaki, D., Izumi, Y., Takahashi, M., Fujimori N., Wing JB., Hayano, T., Asai Y., Bamba, T., Ogawa Y., Furutani-Seiki M., Shirai M., Yamasaki S. Symbiotic bacteria-dependent expansion of MR1-reactive T cells causes autoimmunity in the absence of Bcl11b in lymphocytes.Nature Communications, 13(1):6948, 2022.
  • Motozono, C., Toyoda., M, Zahradnik, J., Saito, A., Nasser, H., Tan, TS., Ngare, I., Kimura, I., Uriu, K., Kosugi, Y., Yue, Y, Shimizu., R, Ito, J., Torii, S., Yonekawa, A., Shimono, N., Nagasaki, Y., Minami, R., Toya, T., Sekiya, N., Fukuhara, T., Matsuura, Y., Schreiber, G., Genotype to Phenotype Japan (G2P-Japan) Consortium, Ikeda, T*., Nakagawa, S*., Ueno, T*., Sato, K*. SARS-CoV-2 spike L452R variant evades cellular immunity and increases infectivity. Cell Host & Microbe 29(7):1124-1136.e11., 2021. *Corresponding equally
  • Takano, T., Motozono, C*., Imai, T., Sonoda, KH., Nakanishi, Y., Yamasaki, S*. Dectin-1 intracellular domain determines species-specific ligand spectrum by modulating receptor sensitivity. J. Biol. Chem. 292(41):16933-16941, 2017. *Corresponding equally
  • Motozono, C#., Pearson, JA#., De Leenheer, E., Rizkallah, PJ., Beck, K., Trimby, A., Sewell, AK., Wong, FS., Cole, DK. Distortion of the Major Histocompatibility Complex Class I Binding Groove to Accommodate an Insulin-derived 10-Mer Peptide. J. Biol. Chem. 290(31): 18924-18933, 2015. #Contributed equally
  • Motozono, C., Bridgeman, JS., Price, DA., Sewell, AK., Ueno, T. Clonotypically similar hybrid αβ T cell receptors can exhibit markedly different surface expression, antigen specificity and cross-reactivity. Clin. Exp. Immunol. 180(3): 560-570, 2014.
  • Motozono, C#, Kuse, N#., Sun, X., Rizkallah, PJ., Fuller, A., Oka, S., Cole, DK., Sewell, AK., Takiguchi, M. Molecular basis of a dominant T cell response to an HIV reverse transcriptase 8-mer epitope presented by the protective allele HLA-B*51:01. J. Immunol. 192(7): 3428-3434, 2014. #Contributed equally
  • Motozono, C., Yokoyama, M., Sato, H., Ueno, T. Cross-reactivity analysis of T cell receptors specific for overlapping HIV-1 Nef epitopes of different lengths. Microbes. Infect. 16(4): 320-327, 2014.
  • Motozono, C., Miles, JJ., Hasan, Z., Gatanaga, H., Meribe, SC., Price, DA., Oka, S., Sewell, AK., Ueno, T. CD8(+) T cell cross-reactivity profiles and HIV-1 immune escape towards an HLA-B35-restricted immunodominant Nef epitope. PLoS One. 8(6): e66152, 2013.
  • Motozono, C., Yanaka, S., Tsumoto, K., Takiguchi, M., Ueno, T. Impact of intrinsic cooperative thermodynamics of peptide-MHC complexes on antiviral activity of HIV-specific CTL. J. Immunol. 182(9): 5528-5536, 2009.