2021 April-July

Date Presenter


21 July , 2021 Takayuki Chikata
Bansal A, et al. LA-E-restricted HIV-1-specific CD8+ T cell responses in natural infection. J Clin Invest. 2021 Aug 16;131(16):e148979. doi: 10.1172/JCI148979.
7 July , 2021 Nozomi Kuse
Nathan A, et al. Structure-guided T cell vaccine design for SARS-CoV-2 variants and sarbecoviruses. Cell. 2021 Aug 19;184(17):4401-4413.e10. doi: 10.1016/j.cell.2021.06.029. Epub 2021 Jun 30.
23 June, 2021 Hung Nguyen The
Gangaev A, et al. Identification and characterization of a SARS-CoV-2 specific CD8 + T cell response with immunodominant features. Nat Commun. 2021 May 10;12(1):2593. doi: 10.1038/s41467-021-22811-y.
26 May, 2021 Takayuki Chikata
Yang H, et al. Incoming HIV virion-derived Gag Spacer Peptide 2 (p1) is a target of effective CD8 + T cell antiviral responses. Cell Rep. 2021 May 11;35(6):109103. doi: 10.1016/j.celrep.2021.109103.
12 May, 2021 Nozomi Kuse
1) Tarke A, et al. Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases. Cell Rep Med. 2021 Feb 16;2(2):100204. doi: 10.1016/j.xcrm.2021.100204.
2) Agerer B, et al. SARS-CoV-2 mutations in MHC-I-restricted epitopes evade CD8 + T cell responses. Sci Immunol. 2021 Mar 4;6(57):eabg6461. doi: 10.1126/sciimmunol.abg6461.
21 April , 2021 Hung Nguyen The
1) Holzemer A, et al. Selection of an HLA-C03:04-Restricted HIV-1 p24 Gag Sequence Variant Is Associated with Viral Escape from KIR2DL3+ Natural Killer Cells: Data from an Observational Cohort in South Africa. PLoS Med. 2015 Nov 17;12(11):e1001900; discussion e1001900.
2) Ziegler MC, et al. HIV-1 evades a Gag mutation that abrogates killer cell immunoglobulin-like receptor binding and disinhibits natural killer cells in infected individuals with KIR2DL2R/HLA-CM03:04R genotype. AIDS. 2021 Jan 1;35(1):151-154. doi: 10.1097/QAD.0000000000002721.
3) Ziegler MC, et al. HIV-1 induced changes in HLA-CM03 : 04-presented peptide repertoires lead to reduced engagement of inhibitory natural killer cell receptors. AIDS. 2020 Oct 1;34(12):1713-1723. doi: 10.1097/QAD.0000000000002596.
7 April , 2021 Yu Zhang
Yang H, et al. HLA-E-restricted, Gag-specific CD8 + T cells can suppress HIV-1 infection, offering vaccine opportunities. Sci Immunol. 2021 Mar 25;6(57):eabg1703.