International Conferences
2009-2010
2010

24) Masafumi Takiguchi, AIDS Vaccine DevelopmentFThe Present and Future The 19th Symposium on the International Medical Cooperation “Vaccine save our century ” (Tokyo, Japan),  November 19 , 2010

23) Masafumi Takiguchi, The role of HIV-1-specific CD8+ T cells in HIV-1-infected HLA-B57/B27-negative Japanese individuals, 11th Kumamoto AIDS Seminar- GCOE joint International Symposium (Kumamoto, Japan) Oct. 6-8, 2010

22) Masao Hashimoto, Shinichi Oka, Masafumi Takiguchi, HIV-1 specific HLA-B*5401-restricted Pol155-specific CTLs include distinct CTL repertoire with different antigen specificity against epitope variant, 11th Kumamoto AIDS Seminar- GCOE joint International Symposium (Kumamoto, Japan) Oct. 6-8, 2010

21) Nozomi Kuse, Yuka Kawashima, Takuya Naruto, Tomohiro Akahoshi, Hiroyuki Gatanaga, Shinichi Oka, Masafumi Takiguchi, Long-term control of HIV-1 infection in HLA-B*5101+ Japanese hemophiliacs, 11th Kumamoto AIDS Seminar- GCOE joint International Symposium (Kumamoto, Japan) Oct. 6-8, 2010

20) Yoshinori Sato, Hiroshi Takata, Sayaka Nagata, and Masafumi Takiguchi, Failure of effector function of human CD8+ T cells in NOD/SCID/Jak3-/- mice transplanted with human CD34+ hematopoietic stem cells, 11th Kumamoto AIDS Seminar- GCOE joint International Symposium (Kumamoto, Japan) Oct. 6-8, 2010

19) Takuya Naruto, Yuka Kawashima, Masafumi Takiguchi, Selection of HLA-B57-associated Gag A146P mutant by HLA-B*4801-resticted CTLs in HLA-B57-negative Japanese cohort, 11th Kumamoto AIDS Seminar- GCOE joint International Symposium (Kumamoto, Japan) Oct. 6-8, 2010

18) Kazutaka Honda, Nan Zheng, Hayato Murakoshi, Masao Hashimoto, Keiko Sakai, Madoka Koyanagi, Takayuki Chikata, Yoshiko Tamura, Borgham M Ali, Hiroyuki Gatanaga , Shinichi Oka, and Masafumi Takiguchi, Selection of HIV-1@escape mutant by HLA-Cw*1202-restricted Pol-specific cytotoxic T lymphocytes having a strong ability to suppress HIV-1 replication, 11th Kumamoto AIDS Seminar- GCOE joint International Symposium (Kumamoto, Japan) Oct. 6-8, 2010

17) Tomohiro Akahoshi, Shinichi Oka, and Masafumi Takiguchi ,HIV-1-specific cytotoxic T lymphocytes having cross-recognition for escape mutation, 11th Kumamoto AIDS Seminar- GCOE joint International Symposium (Kumamoto, Japan) Oct. 6-8, 2010

16) Madoka Koyanagi, Hayato Murakoshi, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi, HIV-1-specific CD4+ T cell response to HIV-1 Nef, Gag and Pol in Japanese cohort, 11th Kumamoto AIDS Seminar- GCOE joint International Symposium (Kumamoto, Japan) Oct. 6-8, 2010

15) Hayato Murakoshi, Hiroyuki Gatanaga, Madoka Koyanagi, Shinichi Oka, and Masafumi Takiguchi, Comprehensive analysis of HIV-1-specific CD8+ T cell responses in chronically HIV-1-infected Japanese cohort, 11th Kumamoto AIDS Seminar- GCOE joint International Symposium (Kumamoto, Japan) Oct. 6-8, 2010

14) Takayuki Chikata, Masao Hashimoto, Yoshiko Tamura, Takuya Naruto, Mohamed Ali Borghan, Sayaka Nagata, Mari Hasegawa, Hiroyuki Gatanaga, Shinichi Oka, Masafumi Takiguchi, HLA-Associated Viral Polymorphism in Chronically HIV-1 Infected Japanese Cohort, 11th Kumamoto AIDS Seminar- GCOE joint International Symposium (Kumamoto, Japan) Oct. 6-8, 2010

13) Kazutaka Honda, Nan Zheng, Hayato Murakoshi, Masao Hashimoto, Keiko Sakai, Madoka Koyanagi, Takayuki Chikata, Yoshiko Tamura, Borgham M Ali, Hiroyuki Gatanaga, Shinichi Oka and Masafumi Takiguchi, Selection of HIV-1@escape mutant by HLA-C-restricted cytotoxic T lymphocytes having a strong ability to suppress HIV-1 replication, AIDS Vaccine 2010 (Atlanta, USA) September 28-October 1, 2010

12) Kazutaka Honda, Nan Zheng, Masao Hashimoto, Keiko Sakai, Takayuki Chikata, Yoshiko Tamura, Borgham M Ali, Hiroyuki Gatanaga, Shinichi Oka and Masafumi Takiguchi, Selection of escape mutant by HLA-C-restricted HIV-1 Pol-specific cytotoxic T lymphocytes having a strong ability to suppress HIV-1 replication, 14th International Congress of Immunology (Kobe, Japan) August 22-27, 2010.@BD Japan Young Investigators' Travel Award

11) Nozomi Kuse, Yuka Kawashima, Hiroyuki Gatanaga, Takuya Naruto, Shinichi Oka and Masafumi Takiguchi, Long term control of HIV-1 replication by Pol283-8-specific CTLs in HLA-B*5101+ solw progressors, 14th International Congress of Immunology (Kobe, Japan) August 22-27, 2010

10j Philip Mwimanzi, Masafumi Takiguchi and Takamasa Ueno, CTL-escape Nef variants influence CCR5 down-regulation and HIV superinfection susceptibility, Keystone symposia|HIV-Vaccines (Banff, Canada) March21-26, 2010

9j Chihiro Motozono, Masafumi Takiguchi and Takamasa Ueno, The cross-reactive capacity of HIV-specific CTLs towards HIV variant antigens is dependent on their cognate peptides, Keystone symposia|HIV-Vaccines (Banff, Canada) March21-26, 2010

8) Masao Hashimoto, Mitsutaka Kitano, Shinichi Oka and Masafumi Takiguchi, Comprehensive analysis of escape mutation from HIV-1-specific cytotoxic T cells restricted by Asian allele HLA-B*5401, Keystone symposia|HIV-Vaccines (Banff, Canada) March21-26, 2010

7) Madoka Koyanagi, Hayato Murakoshi, Hiroyuki Gatanaga, Shinichi Oka and Masafumi Takiguchi, HIV-1 specific CD4+ T cell response against HIV-1 Nef, Gag and Pol in Japanese cohort, Keystone symposia|HIV-Vaccines (Banff, Canada) March21-26, 2010

6) Keiko Sakai, Hiroyuki Gatanaga, Shinichi Oka and Masafumi Takiguchi, Correlation between nadir CD4 counts and skewed distributions of CD4+ T-cell subsets in patients chronically infected with HIV-1, International Young Investigator Symposium 2010 (Kumamoto, Japan) March 4-5, 2010

5) Nan Zheng, Mamoru Fujiwara, Takamasa Ueno, Shinichi Oka and Masafumi Takiguchi, Roles of CD4+ T Cells in the Control of HIV Infection: The Victim Strikes Back, International Young Investigator Symposium 2010 (Kumamoto, Japan) March 4-5, 2010

4) Kazutaka Honda, Nan Zheng, Hayato Murakoshi, Masao Hashimoto, Keiko Sakai, Takayuki Chikata, Yoshiko Tamura, Borgham M Ali, Hiroyuki Gatanaga, Shinichi Oka and Masafumi Takiguchi, Selection of escape mutant by HLA-C-restricted HIV-1 Pol-specific cytotoxic T lymphocytes having a strong ability to suppress HIV-1 replication, International Young Investigator Symposium 2010 (Kumamoto, Japan) March 4-5, 2010

3) Philip Mwimanzi, Ranya Hassan, Shinya Suzu, Masafumi Takiguchi and Takamasa Ueno, The effects of CTL-escape conferring mutations on Nef's pathogenic functions in primary macrophages., International Young Investigator Symposium 2010 (Kumamoto, Japan) March 4-5, 2010

2) Chihiro Motozono, Masafumi Takiguchi and Takamasa Ueno, T cell receptor cross-reactivity toward variant HIV antigens is dependent on cognate peptide specificity, International Young Investigator Symposium (Kumamoto, Japan) March 4-5, 2010

1) Masao Hashimoto, Mitsutaka Kitano, Kazutaka Honda, Hirokazu Koizumi, Sachi Dohki, Shinichi Oka and Masafumi Takiguchi, Comprehensive analysis of escape mutation from HIV-1-specific cytotoxic T cells restricted by Asian allele HLA-B*5401, International Young Investigator Symposium 2010 (Kumamoto, Japan) March 4-5, 2010

2009

23) Keiko Sakai, Hiroyuki Gatanaga, Shinichi Oka, Masafumi Takiguchi, An impact of nadir CD4 counts on skewed frequency distributions of functional subsets in peripheral CD4+ T cells in patients chronically infected with HIV-1, AIDS Vaccine 2009 (Paris, France) Oct. 19-22, 2009

22) Hayato Murakoshi, Hiroyuki Gatanaga, Madoka Koyanagi, Shinichi Oka, and Masafumi Takiguchi, Control of HIV-1 by HIV-1 Pol-specific CD8+ T cells in chronically HIV-1-infected Japanese cohort, AIDS Vaccine 2009 (Paris, France) Oct. 19-22, 2009

21) Masafumi Takiguchi, HLA-B*5101 and HIV infection, 10th Kumamoto AIDS Seminar- GCOE joint International Symposium (Kumamoto, Japan) Sep. 28-29, 2009

20) Takamasa Ueno, Peptide intrinsic factors that influence CTL's antiviral activity, 10th Kumamoto AIDS Seminar- GCOE joint International Symposium (Kumamoto, Japan) Sep. 28-29, 2009

19) Masao Hashimoto, Mitsutaka Kitano, Kazutaka Honda, Hirokazu Koizumi, Sachi Dohki, Shinichi Oka, Masafumi Takiguchi, Selection of escape mutation by Pol154-162-specific cytotoxic T cells among chronically HIV-1-infected HLA-B*5401-positive individuals, 10th Kumamoto AIDS Seminar- GCOE joint International Symposium (Kumamoto, Japan) Sep. 28-29, 2009

18) Hayato Murakoshi, Hiroyuki Gatanaga, Madoka Koyanagi, Shinichi Oka, and Masafumi Takiguchi, Control of HIV-1 by HIV-1 Pol-specific CD8+ T cells in chronically HIV-1-infected Japanese cohort, 10th Kumamoto AIDS Seminar- GCOE joint International Symposium (Kumamoto, Japan) Sep. 28-29, 2009

17) Chihiro Motozono, Masafumi Takiguchi, Takamasa Ueno, The epitopes dictate the cross reactive capacity of HIV-specific CTLs towards variant antigens, 10th Kumamoto AIDS Seminar- GCOE joint International Symposium (Kumamoto, Japan) Sep. 28-29, 2009

16) Hiroshi Takata and Masafumi Takiguchi, Functional and gene expression analysis in human effector CD8+ T cells, 10th Kumamoto AIDS Seminar- GCOE joint International Symposium (Kumamoto, Japan) Sep. 28-29, 2009

15) Keiko Sakai, Hiroyuki Gatanaga, Shinichi Oka, Masafumi Takiguchi, An effect of nadir CD4 counts on the persisting imbalance of CD4+ T-cell subsets in patients chronically infected with HIV-1, 10th Kumamoto AIDS Seminar- GCOE joint International Symposium (Kumamoto, Japan) Sep. 28-29, 2009

14) Yoshinori Sato, Hiroshi Takata, Sayaka Tamaki and Masafumi Takiguchi, Impaired differentiation and function of human CD8+ T cells in humanized mice, 10th Kumamoto AIDS Seminar- GCOE joint International Symposium (Kumamoto, Japan) Sep. 28-29, 2009

13) Kazutaka Honda, Masao Hashimoto, Keiko Sakai, Tomohiro Akahoshi, Shinichi Oka, and Masafumi Takiguchi, Selection of escape mutant by HLA-C-restricted HIV-1-specific cytotoxic T lymphocytes having a strong ability of to suppress HIV-1 replication, 10th Kumamoto AIDS Seminar- GCOE joint International Symposium (Kumamoto, Japan) Sep. 28-29, 2009

12) Nozomi Kuse, Yuka Kawashima, Hiroyuki Gatanaga, Shinichi Oka, Masafumi Takiguchi, Competitive HIV-1 replication suppression assay: selection of HIV-1 escape mutants by HLA-B*5101-restricted Pol283-8-specific CTLs, 10th Kumamoto AIDS Seminar- GCOE joint International Symposium (Kumamoto, Japan) Sep. 28-29, 2009

11) MWIMANZI Philip, Ranya Hassan, Suzu Shinya, TAKIGUCHI Masafumi, UENO Takamasa, The effects of CTL-escape conferring mutations on Nef's pathogenic functions in primary macrophages, 10th Kumamoto AIDS Seminar- GCOE joint International Symposium (Kumamoto, Japan) Sep. 28-29, 2009

10) Nan Zheng, Mamoru Fujiwara, Takamasa Ueno, Shinichi Oka, and Masafumi Takiguchi, Strong ability of Nef-specific CD4+ cytotoxic T cells to suppress HIV-1 replication in HIV-1-infected CD4+ T cells and macrophages, 10th Kumamoto AIDS Seminar- GCOE joint International Symposium (Kumamoto, Japan) Sep. 28-29, 2009

9) Madoka Koyanagi, Hayato Murakoshi, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi, HIV-1 specific cytotoxic CD4+ T cell response against HIV-1 Nef, Gag and Pol, 10th Kumamoto AIDS Seminar- GCOE joint International Symposium (Kumamoto, Japan) Sep. 28-29, 2009

8) Chihiro Motozono, Masafumi Takiguchi, Takamasa Ueno, Cross-reactive capacity of HIV-specific CTLs is dependent on epitopes, 1st HIV Acute Infection Meeting in Boston (Boston, USA) Sep. 22-23, 2009

7) Philip Mwimanzi, Masafumi Takiguchi, and Takamasa Ueno, Susceptibility to HIV superinfection is influenced by CTL-mediated selective pressure on Nef, 1st HIV Acute Infection Meeting in Boston (Boston, USA) Sep. 22-23, 2009

6) Chihiro Motozono, Masafumi Takiguchi, Takamasa Ueno, Specificity-dependent cross reactive capacity of HIV-specific CTLs, The 96th Annual Meeting The American Association of Immunologists (Seattle, USA) May8-12, 2009

5) Hayato Murakoshi, Hiroyuki Gatanaga, Akiko Taki, Shinichi Oka, and Masafumi Takiguchi, HIV-1-specific CD8+ T cell responses in ART-free Japanese cohort, Keystone symposia|HIV Immunobiology (Keystone, USA) March22-27, 2009

4) Takamasa Ueno, Chihiro Motozono, S Yanaka, K Tsumoto, Masafumi Takiguchi, Antiviral activity of HIV-specific cytotoxic T lymphocytes is influenced by intrinsic cooperative thermodynamics of peptide-MHC complexes , Keystone symposia|HIV Immunobiology (Keystone, USA) March22-27, 2009

3) Kazutaka Honda, Hirokazu Koizumi, Keiko Sakai, Zheng Nan, Tomohiro Akahoshi, Shinichi Oka, and Masafumi Takiguchi, A strong ability of HLA-C-restricted HIV-1-specific cytotoxic T lymphocytes to suppress HIV-1 replication and escape mutations from the CTLs, Keystone symposia|HIV Immunobiology (Keystone, USA) March22-27, 2009

2) Nozomi Kuse, Yuka Kawashima, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi, Selection of HIV-1 escape mutants from HIV-1-specific CTLs in HIV-1 replication suppression assay, Keystone symposia|HIV Immunobiology (Keystone, USA) March22-27, 2009

1) Hiroshi Takata and Masafumi Takiguchi, Detailed functional characterization of subsets in human effector CD8+ T cells, Keystone symposia|Immunologic Memory and Host Defense (Keystone, USA) February8-13, 2009

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