14) Atsuko Hachiya, Kazuki Shimane, Stefan G. Sarafianos, Eiichi N. Kodama, Yasuko Sakagami, Fujie Negishi, Hirokazu Koizumi, Hiroyuki Gatanaga, Masao Matsuoka, Masafumi Takiguchi and Shinichi Oka, Mutations in the connection and RNase H subdomains of HIV-1 reverse transcriptase in the antiretroviral treatment-naive patients., Kumamoto AIDS Seminar(Kumamoto, Japan) Sep18-19, 2008

13) Hiroshi Takata and Masafumi Takiguchi, Detailed analysis of functionally distinct human effector CD8+ T cell subsets, Kumamoto AIDS Seminar(Kumamoto, Japan) Sep18-19, 2008

12) Takamasa Ueno, The balance of power: Nef and CTL, Kumamoto AIDS Seminar(Kumamoto, Japan) Sep18-19, 2008

11) Nan Zheng, Mamoru Fujiwara, Shinichi Oka, Masafumi Takiguchi, Killing of HIV-1-infected CD4+ T cells and macrophages by an HIV-1 Nef-specific CD4+ CTL, Kumamoto AIDS Seminar(Kumamoto, Japan) Sep18-19, 2008

10) Chihiro Motozono, Masafumi Takiguchi, Takamasa Ueno, The decay of peptide-MHC complex influences antiviral activity of HIV-specific CTLs, Kumamoto AIDS Seminar(Kumamoto, Japan) Sep18-19, 2008

9) Hirokazu Koizumi, Mamoru Fujiwara, Atsuko Hachiya, Yuka Kawashima, Takamasa Ueno, Shinichi Oka, and Masafumi Takiguchi, Different effects of HIV-1-specific CTLs having a strong ability to suppress HIV-1 replication on selection of escape mutant viruses, Kumamoto AIDS Seminar(Kumamoto, Japan) Sep18-19, 2008

8) Kazutaka Honda, Hirokazu Koizumi, Zheng Nan, Tomohiro Akahoshi, Shinichi Oka, and Masafumi Takiguchi., Selection of escape mutant from HLA-Cw*1202-restricted cytotoxic T lymphocytes having a strong ability to suppress HIV-1 replication, Kumamoto AIDS Seminar(Kumamoto, Japan) Sep18-19, 2008

7) Nozomi Kuse, Yuka Kawashima, Masafumi Takiguchi, Selection of HIV-1 escape mutants from HIV-1-specific CTLs in HIV-1 replication suppression assay, Kumamoto AIDS Seminar(Kumamoto, Japan) Sep18-19, 2008

6) Hayato Murakoshi, Mitsutaka Kitano, Shinichi Oka, Masafumi Takiguchi, Identification of HLA-B*4801-restricted HIV-1-Gag epitopes, Kumamoto AIDS Seminar(Kumamoto, Japan) Sep18-19, 2008

5) Keiko Sakai, Hiroshi Takata, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi, HIV-1-induced homeostatic and developmental dysfunction of CD4+ T-cell subsets, Kumamoto AIDS Seminar(Kumamoto, Japan) Sep18-19, 2008

4) MWIMANZI Philip, FUJIWARA Mamoru, TAKIGUCHI Masafumi, UENO Takamasa, The effects of CTL-escape conferring mutations on Nef's pathogenic functions in primary macrophages, Kumamoto AIDS Seminar(Kumamoto, Japan) Sep18-19, 2008

3) Naoki Kobayashi, Hiroshi Takata and Masafumi Takiguchi, The immature differentiation of human T cells in humanized NOD/SCID/Jak3-/- mice, Kumamoto AIDS Seminar(Kumamoto, Japan) Sep18-19, 2008

2) Chihiro Motozono, Masafumi Takiguchi, and Takamasa Ueno, The effect of TCR-peptide-MHC interactions on antiviral activity and cross-reactive capacity of HIV-specific CTLs, Keystone Symposia-HIV Pathogenesis- (Banff,Canada) March27-April1, 2008

1) Nan Zheng, Mamoru Fujiwara, Shinichi Oka, Masafumi Takiguchi, Perforin-dependent killing of HIV-1-infected macrophages by HIV-1 Nef-specific CD4+ CTLs, Keystone Symposia-HIV Pathogenesis- (Banff,Canada) March27-April1, 2008

25) Masafumi Takiguchi, Control of HIV-1 by HIV-1-specific CTL in vitro and in vivo, Center for AIDS Research, Kumamoto University, 10th Anniversary Symposium (Kumamoto, Japan) November15-16, 2007

24) Takamasa Ueno , The impact of CTL-mediated selective forces on pathogenic functions of HIV-1 Nef , Center for AIDS Research, Kumamoto University, 10th Anniversary Symposium (Kumamoto, Japan) November15-16, 2007

23) Atsuko Hachiya, E. Kodama, S. G. Sarafianos, M. M. Schuckmann, Y. Sakagami, H. Gatanaga, M. Matsuoka, M. Takiguchi, S. Oka.Amino Acid Mutation, N348I in the Connection Subdomain of HIV-1 Reverse Transcriptase (RT), Confers Multi-class Resistance to Nucleoside and Nonnucleoside RT Inhibitors. 8th Annual Symposium Antiviral Drug Resistance 2007 (Richmondo, Virginia, USA) November11-14, 2007

22) Naoki Kobayashi, Hayato Murakoshi, Sachi Douki, Shinichi Oka and Masafumi Takiguchi, Induction of HLA-A2-restricted HCMV immunodominant epitope-specific CTLs in HIV-1-infected and -uninfected individuals with 3 HLA-A*02 subtypes. 8th Annual Symposium Antiviral Drug Resistance 2007 (Richmondo, Virginia, USA) November11-14, 2007

21) Fumichika Matsuki, Ryo Okada, Takaaki Kondo, Hiroshi Takata, Naoki Kobayashi, Masafumi Takiguchi, Identification of human Th17 cells by using multi-color flowcytric analysis, 8th AIDS Seminar in KUMAMOTO(Kumamoto, Japan) September13-14, 2007 .

20) Hiroshi Takata and Masafumi Takiguchi, The functional analysis of subsets in human effector CD8+ T cells, 8th AIDS Seminar in KUMAMOTO(Kumamoto, Japan) September13-14, 2007

19) Takaaki Kondo and Masafumi Takiguchi, Unique cytokine secretion in human memory CD8+ T cells expressing chemokine receptor CCR4, 8th AIDS Seminar in KUMAMOTO(Kumamoto, Japan) September13-14, 2007

18) Atsuko Hachiya, E. Kodama, S. G. Sarafianos, M. M. Schuckmann, Y. Sakagami, H. Gatanaga, M. Matsuoka, M. Takiguchi, S. Oka, Amino Acid Mutation, N348I in the Connection Subdomain of HIV-1 Reverse Transcriptase (RT), Confers Multi-class Resistance to Nucleoside and Nonnucleoside RT Inhibitors, 8th AIDS Seminar in KUMAMOTO(Kumamoto, Japan) September13-14, 2007

17) Chihiro Motozono, Masafumi Takiguchi, Takamasa Ueno, The capacity of antigenic peptides that dictates antiviral activity of Cytotoxic T Lymphocytes, 8th AIDS Seminar in KUMAMOTO(Kumamoto, Japan) September13-14, 2007

16) Murakoshi, H., Kitano, M., Oka, S. and Takiguchi, M., Identification of HLA-B*4801-restricted HIV-1-specific CD8 T cell epitopes by using overlap peptides, 8th AIDS Seminar in KUMAMOTO(Kumamoto, Japan) September13-14, 2007

15) Honda, K., Koizumi, H., Fujiwara, M., Oka, S. and Takiguchi, M., Strong ability of HLA-C*1202-restricted cytotoxic T lymphocytes to suppress HIV-1 replication, 8th AIDS Seminar in KUMAMOTO(Kumamoto, Japan) September13-14, 2007

14) Yagita, Y., Kawashima, Y., Ariumi, Y., Fujiwara, M., Oka, S. and Takiguchi, M., Selection of viral mutations by Pol283-8-specific CTLs in 2 different HLA class I restrictions, 8th AIDS Seminar in KUMAMOTO(Kumamoto, Japan) September13-14, 2007

13) Zheng, N., Oka, S. and Takiguchi, M., Characterization of CD4+ T cell Epitopes of HIV-1 Nef protein, 8th AIDS Seminar in KUMAMOTO(Kumamoto, Japan) September13-14, 2007

12) Kobayashi, N., Murakoshi, H., Douki, S., Oka, S. and Takiguchi, M., Induction of HLA-A2-restricted HCMV immunodominant epitope-specific CTLs in HIV-1-infected and -uninfected individuals with 3 HLA-A*02 subtypes, 8th AIDS Seminar in KUMAMOTO(Kumamoto, Japan) September13-14, 2007

12) Koizumi, H., Iwatani, T., Hachiya, A., Kawashima, Y., Ueno, T., Oka, S. and Takiguchi, M., Ability of HIV-1-specific CTL to suppress HIV-1 replication and selection of escape mutants in chronically HIV-1-infected individuals, 8th AIDS Seminar in KUMAMOTO(Kumamoto, Japan) September13-14, 2007

11) Fujiwara, M., Tanuma, J., Kawashima, Y., Koizumi, H., Honda, K., Oka, S. and Takiguchi, M., Different Ability of Escape Mutant-Specific Cytotoxic T Cells to Suppress Replication of Escape Mutant and Wild-type HIV-1 in New Hosts, 8th AIDS Seminar in KUMAMOTO(Kumamoto, Japan) September13-14, 2007

10) Kawashima, Y., Fujiwara, M., Gatanaga, H., Hachiya, A., Kitano, M., Koizumi, H., Oka, S. and Takiguchi, M., Control of HIV-1 replication by HIV-1-specific CTL in HLA-B*51+ long-term non progressors, 8th AIDS Seminar in KUMAMOTO(Kumamoto, Japan) September13-14, 2007

9) Keiko Sakai and Michael J. Lenardo, Molecular Analysis of HIV-1-induced CD4+ T-lymphocyte cytopathicity, 8th AIDS Seminar in KUMAMOTO(Kumamoto, Japan) September13-14, 2007

8) Takamasa Ueno, Chihiro Motozono, Sachi Douki, Susanne Rauch, Philip Mwimanzi, Oliver T. Fackler, Shinichi Oka, Masafumi Takiguchi, CTL-mediated selective pressure influences dynamic evolution and pathogenic functions of HIV-1 Nef, 8th AIDS Seminar in KUMAMOTO(Kumamoto, Japan) September13-14, 2007

7) Yuichi Yagita, Yuka Kawashima, Yasuo Ariumi, Mamoru Fujiwara, Shinichi Oka, and Masafumi Takiguchi, Accumulation of escape mutants by Pol283-8-specific cytotoxic T lymphocytes in 2 different HLA class I restriction, 4th International AIDS Society Conference 2007(Sydney, Australia) July22-26, 2007

6) Kazutaka Honda, Hirokazu Koizumi, Sachi Dohki, Mistutaka Kitano, Tomomi Iwatani, Shinichi Oka, and Masafumi Takiguchi, Strong ability of HLA-C*1202-restricted cytotoxic T lymphocytes to suppress HIV-1 replication, 4th International AIDS Society Conference 2007(Sydney, Australia) July22-26, 2007

5) Hiroshi Takata and Masafumi Takiguchi, One human effector CD8+ T cell subset retained memory T cell, Keystone Symposia Immunologic Memory (Santa Fe, New Mexico) March 3-8, 2007.

4） Takaaki Kondo and Masafumi Takiguchi, Unique expression and function of chemokine receptor CCR4 on human memory CD8+ T cells, Keystone Symposia Immunologic Memory (Santa Fe, New Mexico) March 3-8, 2007.

3） Mamoru Fujiwara, Tanuma, J., Yuka Kawashima, Hirokazu Koizumi, Kazutaka Honda, Shinichi Oka and Masafumi Takiguchi, Responses of cytotoxic T cells to escape mutation of immunodominant HIV-1 Nef epitope, Keystone Symposia HIV Vaccines(Whistler, Canada) March 25-30, 2007

2） Yuka Kawashima, Mamoru Fujiwara, Hirohisa Gatanaga, Atsuko Hachiya, Mitsutaka Kitano, Shinichi Oka and Masafumi Takiguchi, Control of HIV-1 replication by strong immune pressure via HIV-1-specific cytotoxic T lymphocytes and appearance of lower fitness virus in long-term non-progressing hemophiliacs, Keystone Symposia HIV Vaccines(Whistler, Canada) March 25-30, 2007

1) Atsuko Hachiya, E. Kodama, S. G. Sarafianos, M. Schuckman, M. Matsuoka, M. Takiguchi, H. Gatanaga and S. Oka. A novel mutation, N348I in HIV-1 reverse transcriptase induced by NRTI treatment, confers Nevirapine resistance. 14ｔｈ Conference on retrovirus and opportunistic infections. (Los Angeles, CA, USA) February 25-28, 2007.