大学院生業績 |
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2006-2013 |
| 蜂谷 敦子 （大学院博士課程2008年度修了) |
| ■論文発表 |
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2013 |
Hiroyuki Gatanaga, Hayato Murakoshi, Atsuko Hachiya, Tsunefusa Hayashida, Takayuki Chikata, Hirotaka Ode, Kiyoto Tsuchiya, Wataru Sugiura, Masafumi Takiguchi, and Shinichi Oka, Naturally selected rilpivirine-resistant HIV-1 variants by host cellular immunity, Clinical Infectious Disease, In press |
| 2010 | Hirokazu Koizumi*, Masao Hashimoto*, Mamoru Fujiwara, Hayato Murakoshi, Takayuki Chikata, Mohamed Ali Borghan, Atsuko Hachiya, Yuka Kawashima, Hiroshi Takata, Takamasa Ueno, Shinichi Oka and Masafumi Takiguchi, Different in vivo effects of HIV-1 immunodominant epitope-specific CTLs on selection of escape mutant viruses. J. Virol. 84: 5508-5519, 2010 (* equal contribution) |
| Hiroyuki Gatanaga, Hirotaka Ode, Atsuko Hachiya, Tsunefusa Hayashida, Hironori Sato, Masafumi Takiguchi and Shinichi Oka, Impact of human leukocyte antigen-B*51-restricted cytotoxic T-lymphocyte pressure on mutation patterns of nonnucleoside reverse transcriptase inhibitor resistance. AIDS. 24:F15-22, 2010 | |
| 2009 | Yuka Kawashima, Katja Pfafferott, John Frater, Philippa Matthews, Rebecca Payne, Marylyn Addo, Hiroyuki Gatanaga, Mamoru Fujiwara, Atsuko Hachiya, Hirokazu Koizumi, Nozomi Kuse, Shinichi Oka, Anna Duda, Andrew Prendergast, Hayley Crawford, Alasdair Leslie, Zabrina Brumme, Chanson Brumme, Todd Allen, Christian Brander, Richard Kaslow, James Tang, Eric Hunter, Susan Allen, Joseph Mulenga, Songee Branch, Tim Roach, Mina John, Simon Mallal, Anthony Ogwu, Roger Shapiro, Julia G. Prado, Sarah Fidler, Jonathan Weber, Oliver G. Pybus, Paul Klenerman, Thumbi Ndung’u, Rodney Phillips, David Heckerman, P. Richard Harrigan, Bruce D. Walker, Masafumi Takiguchi*, and Philip Goulder* (*equally contribution) Adaptation of HIV-1 to Human Leukocyte Antigen class I . Nature, 458: 641-645, 2009 |
| Atsuko Hachiya, Kazuki Shimane, Stefan G.Sarafianos, Eiichi N. Kodama, Yasuko Sakagami, Fujie Negishi, Hirokazu Koizumi, Hiroyuki Gatanaga, Masao Matsuoka, Masafumi Takiguchi and Shinichi Oka, Clinical relevance of substitutions in the connection subdomain and RNase H domains of HIV-1 reverse transcriptase from a cohort of antiretroviral treatment-naive patients, Antiviral Research In press | |
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2008 |
Atsuko Hachiya, Eiichi N. Kodama, Stefan G. Sarafianos, Matthew M. Schuckmann, Yasuko Sakagami, Masao Matsuoka, Masafumi Takiguchi, Hiroyuki Gatanaga, Shinichi Oka. Amino Acid Mutation N348I in the Connection Subdomain of HIV-1 Reverse Transcriptase Confers Multi-class Resistance to Nucleoside and Non-nucleoside Reverse Transcriptase Inhibitors. J. Virol., 82:3261-3270 |
| ■学会発表 |
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| 2008 | 蜂谷敦子、嶋根和毅、児玉栄一、小泉寛和、潟永博之、松岡雅雄、滝口雅文、岡慎一．逆転写酵素 connectionとRNase H subdomainの多様性と薬剤感受性に及ぼす影響．第22回日本エイズ学会学術集会・総会(大阪)平成20年11月26日-28日 |
| Atsuko Hachiya, Kazuki Shimane, Stefan G. Sarafianos, Eiichi N. Kodama, Yasuko Sakagami, Fujie Negishi, Hirokazu Koizumi, Hiroyuki Gatanaga, Masao Matsuoka, Masafumi Takiguchi and Shinichi Oka, Mutations in the connection and RNase H subdomains of HIV-1 reverse transcriptase in the antiretroviral treatment-naive patients., 第9回熊本エイズセミナー (熊本) 平成20年9月18-19日 | |
| 2007 | Atsuko Hachiya, E. Kodama, S. G. Sarafianos, M. M. Schuckmann, Y. Sakagami, H. Gatanaga, M. Matsuoka, M. Takiguchi, S. Oka.Amino Acid Mutation, N348I in the Connection Subdomain of HIV-1 Reverse Transcriptase (RT), Confers Multi-class Resistance to Nucleoside and Nonnucleoside RT Inhibitors. 8th Annual Symposium Antiviral Drug Resistance 2007 (Richmondo, Virginia, USA) November11-14, 2007 |
| 蜂谷敦子、香川孝司、岡慎一（2007） CLEIA法を測定原理としたHIV抗体検出試薬の基礎的検討 第56回日本医学検査学会 （宮崎） 5月18日〜19日 | |
| Atsuko Hachiya, E. Kodama, S. G. Sarafianos, M. Schuckman, M. Matsuoka, M. Takiguchi, H. Gatanaga and S. Oka. A novel mutation, N348I in HIV-1 reverse transcriptase induced by NRTI treatment, confers Nevirapine resistance. 14ｔｈ Conference on retrovirus and opportunistic infections. (Los Angeles, CA, USA) February 25-28, 2007. | |
| 2006 | 蜂谷敦子、潟永博之、児玉栄一、松岡雅雄、滝口雅文、岡慎一（2006） NRTIを含む治療中に誘導された新しいネビラピン耐性変異 日本エイズ学会総会（東京） 11月30日〜12月2日 |
| 蜂谷敦子、潟永博之、児玉栄一、松岡雅雄、滝口雅文、岡慎一、(2006)NRTIを含む治療中に 誘導された新しいネビラピン（NVP)耐性変異 第９回白馬シンポジウム（京都）10月12日〜13日 |
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| A. Hachiya, H. Gatanaga, E.
Kodama, M. Matsuoka, M. Takiguchi, S. Oka, Novel mutation, N348I in HIV-1
reverse transcriptase (RT), induced by nucleoside RT inhibitor (NRTI)-treatment,
confers newirapine resistance,
7th AIDS Seminar in Kumamoto. (Kumamoto, Japan) September 21-22, 2006. |
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