大学院生業績 |
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2007- |
| 久世 望 （大学院博士課程2011年度修了） |
| ■論文発表 |
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2016 |
Zhansong Lin, Kimiko Kuroki, Nozomi Kuse, Xiaoming Sun, Tomohiro Akahoshi, Ying Qi, Takayuki Chikata, Takuya Naruto, Madoka Koyanagi, Hayato Murakoshi, Hiroyuki Gatanaga, Shinichi Oka, Mary Carrington, Katsumi Maenaka, Masafumi Takiguchi, HIV-1 control by NK cells via reduced interaction between KIR2DL2 and HLA-C*12:02/C*14:03, Cell Reports 17:2210-2220, 2016 |
| Xiaoming Sun, Yi Shi, Tomohiro Akahoshi, Mamoru Fujiwara, Hiroyuki Gatanaga, Christian Schonbach, Nozomi Kuse, Victor Appay, George F. Gao, Shinichi Oka, and Masafumi Takiguchi, Effects of a single escape mutation on T cell and HIV-1 co-adaptation, Cell Reports, 15:2279-2291, 2016 | |
| Giang Van Tran,* Takayuki Chikata,* Jonathan M. Carson, Hayato Murakoshi, Dung Hoai Nguyen, Yoshiko Tamura, Tomohiro Akahoshi, Nozomi Kuse, Keiko Sakai, Sachiko Sakai, Kyle Cobarrubias, Shinichi Oka, Zabrina L. Brumme, Kinh Van Nguyen, and Masafumi Takiguchi (*Equal contribution), A strong association of HLA-associated Pol and Gag mutations with clinical parameters in HIV-1 subtype A/E infection, AIDS 30:681-689, 2016 | |
| 2015 | Michihiro Hashimoto*, Hesham Nasser*, Farzana Bhuyan*, Nozomi Kuse, Yorifumi Satou, Shigeyoshi Harada, Kazuhisa Yoshimura, Jun-ichi Sakuragi, Kazuaki Monde, Yosuke Maeda, Sarah Welbourn, Klaus Strebel, Ekram W. Abd El-Wahab, Mitsue Miyazaki, Shinichiro Hattori, Nopporn Chutiwitoonchai, Masateru Hiyoshi, Shinichi Oka, Masafumi Takiguchi**, and Shinya Suzu** (*, **Equal contribution). Fibrocytes differ from macrophages but can be infected with HIV-1, J. Immunol. 195(9):4341-50, 2015 |
| Nozomi Kuse*, Mohammad Arif Rahman*, Hayato Murakoshi*, Giang Van Tran, Takayuki Chikata, Madoka Koyanagi, Kinh Van Nguyen, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi, Different Effects of Nonnucleoside Reverse Transcriptase Inhibitor Resistance Mutations on Cytotoxic T Lymphocyte Recognition between HIV-1 Subtype B and Subtype A/E Infections (*Equal contribution), J. Virol. 89:7363-7372, 2015 | |
| 2014 | Nozomi Kuse, Tomohiro Akahoshi, Hiroyuki Gatanaga, Takamasa Ueno, Shinichi Oka, and Masafumi Takiguchi, Selection of TI8-8V Mutant Associated with Long-Term Control of HIV-1 by Cross-Reactive HLA-B*51:01-restricted Cytotoxic T Cells, J. Immunol. 193:4814-4822, 2014 |
| Xiaoming Sun*, Mamoru Fujiwara*, Yi Shi*, Nozomi Kuse, Hiroyuki Gatanaga, Victor Appay, George F. Gao, Shinichi Oka, and Masafumi Takiguchi (* Equal contribution), Superimposed epitopes restricted by the same HLA molecule drive distinct HIV-specific CD8+ T cell repertoires. J. Immunol. 193:77-84, 2014 | |
| Chihiro Motozono*, Nozomi Kuse*, Xiaoming Sun, Pierre J. Rizkallah, Anna Fuller, Shinichi Oka, David K. Cole, Andrew K. Sewell,and Masafumi Takiguchi (*Equal contribution), Molecular basis of a dominant T-cell response to an HIV reverse transcriptase 8-mer epitope presented by the protective allele HLA-B*51:01, J. Immunol. 192:3428-3434, 2014 | |
2013 |
Gabriel Espinosa, Javier A. Collado, Erika Scholz, Anna Mestre-Ferrer, Nozomi Kuse, Masafumi Takiguchi, Montserrat Carrascal, Francesc Canals, Ricardo Pujol-Borrell, Dolores Jaraquemada, and Inaki Alvarez, Peptides presented by HLA class I molecules in the human thymus, J. Proteomics, 94:23-26, 2013 |
| Kristin Ladell*, Masao Hashimoto*, Maria Candela Iglesias*, Pascal G. Wilmann*, James E. McLaren, Stephanie Gras, Takayuki Chikata, Nozomi Kuse, Solene Fastenackels, Emma Gostick, John S. Bridgeman, Vanessa Venturi, Zaina Ait Arkoub, Henri Agut, David J. van Bockel, Jorge R. Almeida, Daniel C. Douek, Laurence Meyer, Alain Venet, Masafumi Takiguchi**, Jamie Rossjohn**, David A. Price** and Victor Appay** (*,** Equal contribution), A molecular basis for the control of preimmune escape variants by HIV-specific CD8+ T cells. Immunity. 38:425-436, 2013 | |
| Yuichi Yagita*, Nozomi Kuse*, Kimiko Kuroki*, Hiroyuki Gatanaga, Jonathan M. Carlson, Takayuki Chikata, Zabrina L. Brumme, Hayato Murakoshi, Tomohiro Akahoshi, Nico Pfeifer, Simon Mallal, Mina John, Toyoyuki Ose, Haruki Matsubara, Ryo Kanda, Yuko Fukunaga, Kazutaka Honda, Yuka Kawashima, Yasuo Ariumi, Shinichi Oka, Katsumi Maenaka, and Masafumi Takiguchi (*Equal contribution), Distinct HIV-1 Escape Patterns Selected by Cytotoxic T Cells with Identical Epitope Specificity, J. Virol. 87:2253-2263, 2013 | |
2011 |
YongHong Zhang, YanChun Peng, HuiPing Yan, Keyi Xu, Masumichi Saito, Hao Wu, XinYue Chen, Srinika Ranasinghe, Nozomi Kuse, Tim Powell, Yan Zhao, WeiHua Li, Xin Zhang, Xia Feng, Ning Li, Aleksandra Leligdowicz, XiaoNing Xu, Mina John, Masafumi Takiguchi, Andrew McMichael, Sarah Rowland-Jones, and Tao Dong: Multilayered Defense in HLA-B51-Associated HIV Viral Control, J. Immunol. 187:684-691, 2011 |
2010 |
Yuka Kawashima*, Nozomi Kuse*, Hiroyuki Gatanaga*, Takuya Naruto, Mamoru Fujiwara, Sachi Dohki, Tomohiro Akahoshi, Katsumi Maenaka, Philip Goulder, Shinichi Oka, and Masafumi Takiguchi, Long-term control of HIV-1 in hemophiliacs carrying slow-progressing allele HLA-B*5101. J. Virol. 84:7151-7160, 2010 (* equal contribution) |
2009 |
Yuka Kawashima, Katja Pfafferott, John Frater, Philippa Matthews, Rebecca Payne, Marylyn Addo, Hiroyuki Gatanaga, Mamoru Fujiwara, Atsuko Hachiya, Hirokazu Koizumi, Nozomi Kuse, Shinichi Oka, Anna Duda, Andrew Prendergast, Hayley Crawford, Alasdair Leslie, Zabrina Brumme, Chanson Brumme, Todd Allen, Christian Brander, Richard Kaslow, James Tang, Eric Hunter, Susan Allen, Joseph Mulenga, Songee Branch, Tim Roach, Mina John, Simon Mallal, Anthony Ogwu, Roger Shapiro, Julia G. Prado, Sarah Fidler, Jonathan Weber, Oliver G. Pybus, Paul Klenerman, Thumbi Ndung’u, Rodney Phillips, David Heckerman, P. Richard Harrigan, Bruce D. Walker, Masafumi Takiguchi*, and Philip Goulder* (*equally contribution) Adaptation of HIV-1 to Human Leukocyte Antigen class I . Nature, 458:641-645, 2009 |
| ■学会発表 |
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| 2016 | Nozomi Kuse, Xiaoming Sun, Tomohiro Akahoshi, Anna Lissina, Victor Appay, and Masafumi Takiguchi, Functional analysis of HIV-1-specific CD8+ T cells primed in vitro from naive T cells, 2nd Kumamoto IRCMS International Symposium and 17th Kumamoto AIDS Seminar (Kumamoto, Japan), October 31 - November 2, 2016 |
| Nozomi Kuse, Xiaoming Sun, Tomohiro Akahoshi, Anna Lissina, Victor Appay, and Masafumi Takiguchi, In Vitro Priming of HIV-1-specific CD8+ T Cells from Naive T Cells (Chicago, USA), October 17-21, 2016 | |
| 2015 |
Nozomi Kuse, Xiaoming Sun, Tomohiro Akahoshi, and Masafumi Takiguchi, Immature function of HIV-1-specific CD8+ T cells elicited from HIV-1-seronegative donors, 第44回日本免疫学会学術集会（札幌）, 2015年11月18-20日 |
| 2014 |
Nozomi Kuse, Chihiro Motozono, Xiaoming Sun, Tomohiro Akahoshi, Takamasa Ueno, and Masafumi Takiguchi, Long-term control of HIV-1 by two cross-reactive HLA-B*51:01-restricted CTLs, 第43回日本免疫学会学術集会（京都）, 2014年12月10-12日 |
| Nozomi Kuse, Chihiro Motozono, Xiaoming Sun, Tomohiro Akahoshi, Takamasa Ueno, Pierre J. Rizkallah, Anna Fuller, David K. Cole, Andrew K. Sewell, Hiroyuki Gatanaga, , Shinichi Oka, and Masafumi Takiguchi, Long-term control of HIV-1 by two cross-reactive HLA-B*51:01-restricted CTLs, 15th KUMAMOTO AIDS Seminar (Kumamoto, Japan) October 1-3, 2014 | |
| 久世 望, 本園 千尋, Xiaoming Sun, 赤星 智寛, 上野 貴将, Pierre J. Rizkallah, Anna Fuller, David K. Cole, Andrew K. Sewell, 潟永 博之, 岡 慎一, 滝口 雅文, 長期未発症でみられるHLA-B*51:01拘束性TI８特異的CTLの解析, 第16回白馬シンポジウム （熊本）, 2014年6月13-14日 | |
| 2013 | Nozomi Kuse, Tomohiro Akahoshi and Masafumi Takiguchi, Control of HIV-1 by Pol283-8-specific CTLs in HLA-B*51:01+long-term non progressors, 第42回日本免疫学会学術集会（千葉）, 2013年12月11-13日 |
| Nozomi Kuse, Tomohiro Akahoshi, Hiroyuki Gatanaga, Shinichi Oka and Masafumi Takiguchi, Control of HIV-1 by Pol283-8-specific CTLs in HLA-B*51:01+long-term non progressors, 14th KUMAMOTO AIDS Seminar (Kumamoto, Japan) October 29-31, 2013 | |
| Nozomi Kuse, Tomohiro Akahoshi, Hiroyuki Gatanaga, Shinichi Oka and Masafumi Takiguchi, Selection of Pol283-8V Mutant by Pol283-8-specific CTLs in HLA-B*51:01+Long-Term Non Progressors, AIDS Vaccine 2013 (Barcelona, Spain) October 7-10, 2013 | |
| 2012 |
Nozomi Kuse, Tomohiro Akahoshi, Kimiko Kuroki, Katsumi Maenaka, and Masafumi Takiguchi, Distinct HIV-1 Immune Escape Patterns Selected by CTLs with Identical Epitope Specificity but Different HLA class I Restrictions, 第41回日本免疫学会学術集会（神戸）, 2012年12月5日-7日 |
| Nozomi Kuse, Yuichi Yagita, Kimiko Kuroki, Hiroyuki Gatanaga, Jonathan M.Carlson, Takayuki Chikata, Zabrina L. Brumme, Tomohiro Akahoshi, Nico Pfeifer, Simon Mallal, Mina John, Toyoyuki Ose, Haruki Matsubara, Ryo Kanda, Yuko Fukunaga, Yuka Kawashima, Yasuo Ariumi, Shinichi Oka, Katsumi Maenaka, and Masafumi Takiguchi, Distinct HIV-1 Escape Patterns Selected by CTLs with Identical Epitope Specificity, 13th KUMAMOTO AIDS Seminar-GCOE Joint International Symposium (Kumamoto, Japan) October24-26, 2012 | |
| 2011 |
久世 望, 滝口 雅文, 日本人血友病患者におけるHLA-B*51:01陽性長期未発症者で見られるPol283-8I-特異的CTLによるPol283-8V変異体の選択/Selection of Pol283-8V mutant by Pol283-8I-specific CTLs in longterm non progressors (LTNPs) of HLA-B*51:01+Japanese hemophiliacs, 第40回日本免疫学会学術集会（千葉）, 2011年11月27-29日 |
| Nozomi Kuse, Tomohiro Akahoshi, Yuka Kawashima, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi, Selection of Pol283-8V mutant by Pol283-8-specific CTLs in long-term non progressors of HLA-B*51:01+Japanese hemophiliacs, 12th KUMAMOTO AIDS Seminar-GCOE Joint International Symposium (Kumamoto, Japan) October19-21, 2011 | |
| 2010 |
Nozomi Kuse, Yuka Kawashima, Takuya Naruto, Tomohiro Akahoshi, Hiroyuki Gatanaga, Shinichi Oka, Masafumi Takiguchi, Long-term control of HIV-1 infection in HLA-B*5101+ Japanese hemophiliacs, 11th Kumamoto AIDS Seminar- GCOE joint International Symposium (Kumamoto, Japan) Oct. 6-8, 2010 |
| Nozomi Kuse, Yuka Kawashima, Hiroyuki Gatanaga, Takuya Naruto, Shinichi Oka and Masafumi Takiguchi, Long term control of HIV-1 replication by Pol283-8-specific CTLs in HLA-B*5101+ solw progressors, 14th International Congress of Immunology (Kobe, Japan) August 22-27, 2010 | |
| 2009 |
久世望, 川島夕佳, 潟永博之, 岡慎一, 滝口雅文, HLA-B*5101拘束性 CTLによるHIV-1逃避変異体の選択, 第23回日本エイズ学会学術集会・総会（名古屋）2009年11月26-28日 |
| Nozomi Kuse, Yuka Kawashima, Hiroyuki Gatanaga, Shinichi Oka, Masafumi Takiguchi, Competitive HIV-1 replication suppression assay: selection of HIV-1 escape mutants by HLA-B*5101-restricted Pol283-8-specific CTLs, 10th Kumamoto AIDS Seminar- GCOE joint International Symposium (Kumamoto, Japan) Sep. 28-29, 2009 | |
| Nozomi Kuse, Yuka Kawashima, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi, Selection of HIV-1 escape mutants from HIV-1-specific CTLs in HIV-1 replication suppression assay, Keystone symposia−HIV Immunobiology (Keystone, USA) March22-27, 2009 | |
| 2008 |
久世望, 川島夕佳, 滝口雅文, In vitro実験系におけるHIV-1特異的CTLによる逃避変異体ウイルスの選択, 第56回ウイルス学会学術集会（岡山）2008年10月26-28日 |
| Nozomi Kuse, Yuka Kawashima, Masafumi Takiguchi, Selection of HIV-1 escape mutants from HIV-1-specific CTLs in HIV-1 replication suppression assay, 第9回熊本エイズセミナー (熊本) 2008年9月18-19日 | |
| 2007 |
久世望、川島夕佳、滝口雅文、 In vitro実験系におけるHIV-1特異的CTLによる逃避変異体ウイルスの選択 第21回日本エイズ学会学術集会(広島) 2007年11月28日-30日 |
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