2015

Hashimoto M, Nasser N, Bhuyan F, Kuse N, Satou Y, Harada S, Yoshimura K, Sakuragi J, Monde K, Maeda Y, Welbourn S, Strebel K, Abd El-Wahab EW, Miyazaki M, Hattori S, Chutiwitoonchai N, Hiyoshi M, Oka S, Takiguchi M, Suzu S. Fibrocytes differ from macrophages but can be infected with HIV-1. J Immunol., in press.

Komohara Y, Morita T, Annan DA, Horlad H, Ohnishi K, Yamada S, Nakayama T, Kitada S, Suzu S, Kinoshita I, Dosaka-Akita H, Akashi K, Takeya M, Jinushi M.
The Coordinated Actions of TIM-3 on Cancer and Myeloid Cells in the Regulation of Tumorigenicity and Clinical Prognosis in Clear Cell Renal Cell Carcinomas. Cancer Immunol Res., in press.

2014

Hashimoto M, Nasser H, Chihara T, Suzu S. Macropinocytosis and TAK1 mediate anti-inflammatory to pro-inflammatory macrophage differentiation by HIV-1 Nef. Cell Death Dis. 2014 May 29;5:e1267.

Osman A, Bhuyan F, Hashimoto M, Nasser H, Maekawa T, Suzu S. M-CSF inhibits anti-HIV-1 activity of IL-32 but they enhance M2-like phenotypes of macrophages. J Immunol. 2014 Jun 1;192(11):5083-9.

Yamashina T, Baghdadi M, Yoneda A, Kinoshita I, Suzu S, Dosaka-Akita H, Jinushi M. Cancer stem-like cells derived from chemoresistant tumors have a unique capacity to prime tumorigenic myeloid cells. Cancer Res. 2014 May 15;74(10):2698-709.

Kariya R, Taura M, Suzu S, Kai H, Katano H, Okada S. HIV protease inhibitor Lopinavir induces apoptosis of primary effusion lymphoma cells via suppression of NF-kB pathway. Cancer Lett. 2014 Jan;342(1):52-9.

2013

Hiyoshi M, Hashimoto M, Yukihara M, Bhuyan F, Suzu S. M-CSF receptor mutations in hereditary diffuse leukoencephalopathy with spheroids impair not only kinase activity but also surface expression. Biochem Biophys Res Commun. 2013 Nov 1;440(4):589-93.

Chutiwitoonchai N, Hiyoshi M, Hiyoshi-Yoshidomi Y, Hashimoto M, Tokunaga K, Suzu S. Characteristics of IFITM, the newly identified IFN-inducible anti-HIV-1 family proteins. Microbes Infect. 2013 Apr;15(4):280-90

2012

Komohara Y, Hasita H. Ohnishi K, Fujiwara Y, Bai B, Nakagawa T, Suzu S, Nakamura H, Kuratsu J, Takeya M. Importance of direct macrophage-tumor interaction on progression of human glioma. Cancer Sci. 2012 Dec;103(12):2165-72 .

Chihara T, Hashimoto M, Osman A, Hiyoshi-Yoshidomi Y, Suzu I, Chutiwitoonchai N, Hiyoshi M, Okada S, Suzu S. HIV-1 Proteins Preferentially Activate Anti-Inflammatory M2-Type Macrophages. J Immunol. 2012 Apr 15;188(8):3620-7.

Hiyoshi M, Takahashi-Makise N, Yoshidomi Y, Chutiwitoonchai N, Chihara T, Okada M, Nakamura N, Okada S, Suzu S. HIV-1 Nef perturbs the function, structure, and signaling of the Golgi through the Src kinase Hck. J Cell Physiol. 2012 Mar;227(3):1090-7.

2011

Komohara Y, Hasita H, Ohnishi K, Fujiwara Y, Suzu S, Eto M, Takeya M. Macrophage infiltration and its prognostic relevance in clear cell renal cell carcinoma. Cancer Sci. 2011 Jul;102(7):1424-31.

Mwimanzi P, Hasan Z, Hassan R, Suzu S, Takiguchi M, Ueno T. Effects of naturally-arising HIV Nef mutations on cytotoxic T lymphocyte recognition and Nef's functionality in primary macrophages. Retrovirology. 2011 Jun 22;8:50.

Ono A, Hattori S, Kariya R, Iwanaga S, Taura M, Harada H, Suzu S, Okada S. Comparative study of human hematopoietic cell engraftment into BALB/c and C57BL/6 strain of rag-2/jak3 double-deficient mice. J Biomed Biotechnol. 2011;2011:539748.

Chutiwitoonchai N, Hiyoshi M, Mwimanzi P, Ueno T, Adachi A, Ode H, Sato H, Fackler OT, Okada S, Suzu S. The identification of a small molecule compound that reduces HIV-1 Nef-mediated viral infectivity enhancement. PLoS One. 2011;6(11):e27696.

2010

Chihara T, Suzu S (correspondance), Hassan R, Chutiwitoonchai N, Hiyoshi M, Motoyoshi K, Kimura F, Okada S. IL-34 and M-CSF share the receptor Fms but are not identical in biological activity and signal activation. Cell Death Differ. 2010 Dec;17(12):1917-27.

Dikeakos JD, Atkins KM, Thomas L, Emert-Sedlak L, Byeon IJ, Jung J, Ahn J, Wortman MD, Kukull B, Saito M, Koizumi H, Williamson DM, Hiyoshi M, Barklis E, Takiguchi M, Suzu S, Gronenborn AM, Smithgall TE, Thomas G. Small molecule inhibition of HIV-1-induced MHC-I down-regulation identifies a temporally regulated switch in Nef action. Mol Biol Cell. 2010 Oct 1;21(19):3279-92.

Seubwai W, Vaeteewoottacharn K, Hiyoshi M, Suzu S, Puapairoj A, Wongkham C, Okada S, Wongkham S. Cepharanthine exerts antitumor activity on cholangiocarcinoma by inhibiting NF-kappaB. Cancer Sci. 2010 Jul;101(7):1590-5.

Towata T, Komizu Y, Suzu S, Matsumoto Y, Ueoka R, Okada S. Hybrid liposomes inhibit the growth of primary effusion lymphoma in vitro and in vivo. Leuk Res. 2010 Jul;34(7):906-11.

Towata T, Komizu Y, Kariya R, Suzu S, Matsumoto Y, Kobayashi N, Wongkham C, Wongkham S, Ueoka R, Okada S. Hybrid liposomes inhibit the growth of cholangiocarcinoma by induction of cell cycle arrest in G1 phase. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3680-2.

Towata T, Komizu Y, Suzu S, Ueoka R, Okada S. Highly selective fusion and accumulation of hybrid liposomes into primary effusion lymphoma cells along with induction of apoptosis. Biochem Biophys Res Commun. 2010 Mar 12;393(3):445-8.

Dessouki O, Kamiya Y, Nagahama H, Tanaka M, Suzu S, Sasaki Y, Okada S. Chronic hepatitis C viral infection reduces NK cell frequency and suppresses cytokine secretion: Reversion by anti-viral treatment. Biochem Biophys Res Commun. 2010 Mar 5;393(2):331-7.

2009

Hassan R, Suzu S, Hiyoshi M, Takahashi-Makise N, Ueno T, Agatsuma T, Akari H, Komano J, Takebe Y, Motoyoshi K, Okada S. Dys-regulated activation of a Src tyroine kinase Hck at the Golgi disturbs N-glycosylation of a cytokine receptor Fms. J Cell Physiol. 2009 Nov;221(2):458-68.

Takahashi-Makise N, Suzu S, Hiyoshi M, Ohsugi T, Katano H, Umezawa K, Okada S. Biscoclaurine alkaloid cepharanthine inhibits the growth of primary effusion lymphoma in vitro and in vivo and induces apoptosis via suppression of the NF-kappaB pathway. Int J Cancer. 2009 Sep 15;125(6):1464-72.

Hattori S, Ide K, Nakata H, Harada H, Suzu S, Ashida N, Kohgo S, Hayakawa H, Mitsuya H, Okada S. Potent activity of a nucleoside reverse transcriptase inhibitor, 4'-ethynyl-2-fluoro-2'-deoxyadenosine, against human immunodeficiency virus type 1 infection in a model using human peripheral blood mononuclear cell-transplanted NOD/SCID Janus kinase 3 knockout mice. Antimicrob Agents Chemother. 2009 Sep;53(9):3887-93.

2008

Murakami T, Harada H, Suico MA, Shuto T, Suzu S, Kai H, Okada S. Ephedrae herba, a component of Japanese herbal medicine Mao-to, efficiently activates the replication of latent human immunodeficiency virus type 1 (HIV-1) in a monocytic cell line. Biol Pharm Bull. 2008 Dec;31(12):2334-7.

Okada S, Harada H, Ito T, Saito T, Suzu S. Early development of human hematopoietic and acquired immune systems in new born NOD/Scid/Jak3null mice intrahepatic engrafted with cord blood-derived CD34 + cells. Int J Hematol. 2008 Dec;88(5):476-82.

Hiyoshi M, Suzu S (equal contribution), Yoshidomi Y, Hassan R, Harada H, Sakashita N, Akari H, Motoyoshi K, Okada S. Interaction between Hck and HIV-1 Nef negatively regulates cell surface expression of M-CSF receptor. Blood. 2008 Jan 1;111(1):243-50.

2007

Yamamoto K, Suzu S, Yoshidomi Y, Hiyoshi M, Harada H, Okada S. Erythroblasts highly express the ABC transporter Bcrp1/ABCG2 but do not show the side population (SP) phenotype. Immunol Lett. 2007 Nov 30;114(1):52-8.

Harada H, Goto Y, Ohno T, Suzu S, Okada S. Proliferative activation up-regulates expression of CD4 and HIV-1 co-receptors on NK cells and induces their infection with HIV-1. Eur J Immunol. 2007 Aug;37(8):2148-55.

Suzu S, Hiyoshi M, Yoshidomi Y, Harada H, Takeya M, Kimura F, Motoyoshi K, Okada S. M-CSF-mediated macrophage differentiation but not proliferation is correlated with increased and prolonged ERK activation. J Cell Physiol. 2007
Aug;212(2):519-25.

2005

Harada H, Suzu S, Ito T, Okada S. Selective expansion and engraftment of human CD16+ NK cells in NOD/SCID mice. Eur J Immunol. 2005 Dec;35(12):3599-609.

Harada H, Suzu S, Hayashi Y, Okada S. BT-IgSF, a novel immunoglobulin superfamily protein, functions as a cell adhesion molecule. J Cell Physiol. 2005 Sep;204(3):919-26.

Suzu S, Harada H, Matsumoto T, Okada S. HIV-1 Nef interferes with M-CSF receptor signaling through Hck activation and inhibits M-CSF bioactivities. Blood. 2005 Apr 15;105(8):3230-7.

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