熊本エイズセミナー

8th AIDS Seminar in KUMAMOTO
第８回熊本エイズセミナープログラム

■　Poster Session
P-1 門出　和精熊本大学大学院医学薬学研究部感染防御学 Kazuaki Monde, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan Gp120 V3-dependent impairment of R5 HIV-1 infectivity due to virion incorporated CCR5 P-2 阪井　恵子熊本大学エイズ学研究センターウイルス制御分野 / Laboratory of Immunology, NIAID, NIH, Bethesda, MD, USA Keiko Sakai, Center for AIDS Research, Kumamoto University, Kumamoto, Japan / Laboratory of Immunology, NIAID, NIH, Bethesda, MD, USA Molecular Analysis of HIV-1-induced CD4+ T-lymphocyte cytopathicity P-3 泉　泰輔京都大学大学院医学研究科血液・腫瘍内科 Taisuke Izumi, Graduate School of Medicine, Kyoto University, Kyoto, Japan MDM2 promotes the ubiquitination and degradation of HIV-1 Vif P-4 北山　裕子京都大学ウイルス研究所感染病態研究領域 Hiroko Kitayama, Institute for Virus Research, Kyoto University Kyoto, Japan HIV-1 Vpr inhibits axon formation that leads to impaired repairment of synaptodendritic connections through induction of mitochondrial dysfunction P-5 大石　真久大阪大学微生物病研究所ウイルス感染制御分野 Masahisa Ohishi, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan A study of the relationship between genomic RNA dimerization and maturation of virus particle in HIV-1 P-6 木村　哲也熊本大学大学院医学薬学研究部感染制御学 Tetsuya Kimura, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan Correspondence between Structure and function of HIV-1 Env protein P-7 遊佐　敬介熊本大学大学院医学薬学研究部感染防御学 Keisuke Yusa, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan Characterization of CCR5 dependent replication of HIV-1V3L#25 P-8 柴田　潤二熊本大学エイズ学研究センター病態制御分野 Junji Shibata, Center for AIDS Research, Kumamoto University, Kumamoto, Japan The single mutation in V2 domain affects quaternary structure of trimer gp120 and dramatically increases the sensitivity of primary human immunodeficiency virus type 1 isolates to neutralizing antibodies. P-9 西田　吉辰熊本大学エイズ学研究センター病態制御分野 Yoshitatsu Nishida, Center for AIDS Research, Kumamoto University, Kumamoto, Japan Broad neutralization against the HIV-1 subtype B panel of reference strains by　human monoclonal antibodies established from an HIV-1infected long-term non-progressor P-10 畑田　万紀子熊本大学エイズ学研究センター病態制御分野 Makiko Hatada, Center for AIDS Research, Kumamoto University, Kumamoto, Japan HIV-1BaL mutants escaping neutralization from a potent neutralizing anti-V3 monoclonal antibody KD-247 P-11 三根　明熊本大学大学院医学薬学研究部薬学生化学分野 Akira Mine, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan Human immunodeficiency virus-induced apoptosis of human breast cancer cells via CXCR4 is mediated by the viral envelope protein but does not require CD4 P-12 藤原　守熊本大学エイズ学研究センターウイルス制御分野 Mamoru Fujiwara, Center for AIDS Research, Kumamoto University, Kumamoto, Japan Different Ability of Escape Mutant-Specific Cytotoxic T Cells to Suppress Replication of Escape Mutant and Wild-type HIV-1 in New Hosts P-13 小泉　寛和熊本大学エイズ学研究センターウイルス制御分野 Hirokazu Koizumi, Center for AIDS Research, Kumamoto University, Kumamoto, Japan Ability of HIV-1-specific CTL to suppress HIV-1 replication and selection of escape mutants in chronically HIV-1-infected individuals P-14 本園　千尋熊本大学エイズ学研究センターウイルス制御分野 Chihiro Motozono, Center for AIDS Research, Kumamoto University, Kumamoto, Japan The capacity of antigenic peptides that dictates antiviral activity of Cytotoxic T Lymphocytes P-15 吉富　友香熊本大学エイズ学研究センター予防開発分野 Yuka Yoshidomi, Center for AIDS Research, Kumamoto University, Kumamoto, Japan Interaction between Hck and HIV-1 Nef negatively regulates cell surface expression of M-CSF receptor P-16 星野　重樹国立国際医療センター研究所　難治性疾患研究部 Shigeki Hoshino, International Medical Center of Japan, Tokyo, Japan HIV-1 Vpr induced IL-6 production from monocytes / macrophages via IKK, JNK and p38 pathways P-17 光木　裕也国立感染症研究所　免疫部第一室 Yu-ya Mitsuki, AIDS Research Center, National Institute of Infectious Diseases, Kumamoto, Japan Application of DsRed expressing virus for the analysis of HIV-1 transmission from dendritic cells to T cells. P-18 松永雄亮熊本大学大学院医学薬学研究部免疫識別学分野 Yusuke Matsunaga,Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan Induction of respiratory syncytial virus antigen specific CTL by utilizing TAP1 gene disrupted allogeneic mouse ES cell-derived dendritic cells P-19 小川　陽一山梨大医学部皮膚科学教室 Yoichi Ogawa, Faculty of medicine, University of Yamanashi, Yamanashi, Japan Human Langerhans cells express the functional Toll-like receptors at protein levels P-20 小林　直樹熊本大学エイズ学研究センターウイルス制御分野 Naoki Kobayashi, Center for AIDS Research, Kumamoto University, Kumamoto, Japan Induction of HLA-A2-restricted HCMV immunodominant epitope-specific CTLs in HIV-1-infected and -uninfected individuals with 3 HLA-A02 subtypes P-21* Nan Zheng 熊本大学エイズ学研究センターウイルス制御分野 Nan Zheng, Center for AIDS Research, Kumamoto University, Kumamoto, Japan Characterization of CD4+ T cell Epitopes of HIV-1 Nef protein P-22 八木田　悠一熊本大学エイズ学研究センターウイルス制御分野 Yuichi Yagita, Center for AIDS Research, Kumamoto University, Kumamoto, Japan Selection of viral mutations by Pol283-8-specific CTLs in 2 different HLA class I restrictions P-23 本田　一貴熊本大学エイズ学研究センターウイルス制御分野 Kazutaka Honda, Center for AIDS Research, Kumamoto University, Kumamoto, Japan Strong ability of HLA-C1202-restricted cytotoxic T lymphocytes to suppress HIV-1 replication P-24* 川島　夕佳熊本大学エイズ学研究センターウイルス制御分野 Yuka Kawashima, Center for AIDS Research, Kumamoto University, Kumamoto, Japan Control of HIV-1 replication by HIV-1-specific CTL in HLA-B51+ long-term non progressors P-25* 村越　勇人熊本大学エイズ学研究センターウイルス制御分野 Hayato Murakoshi, Center for AIDS Research, Kumamoto University, Kumamoto, Japan Identification of HLA-B4801-restricted HIV-1-specific CD8 T cell epitopes by using overlap peptides P-26* 蜂谷　敦子熊本大学エイズ学研究センターウイルス制御分野 / 国立国際医療センター　エイズ治療・研究開発センター Atsuko Hachiya, Center for AIDS Research, Kumamoto University, Kumamoto, Japan / AIDS Clinical Center, International Medical Center of Japan, Tokyo, Japan Amino acid mutation, N348I in the connection subdomain of HIV-1 reverse transcriptase (RT), confers multi-class resistance to nucleoside and nonnucleoside RT inhibitors P-27 青木　学熊本大学大学院医学薬学研究部血液内科学分野 Manabu Aoki, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan TTNTRNS: An amino acid insert near the p17/p24 Gag cleavage site associated with resistance to protease inhibitors P-28 山田　裕子東京医科歯科大学生体材料工学研究所 Yuko Yamada, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo, Japan Development of chemokine receptor CXCR4 antagonists as X4-HIV entry inhibitors P-29 林田　庸総国立国際医療センターエイズ治療・研究開発センター　臨床研究開発部　治療開発室 Hayashida Tsunefusa, AIDS Clinical Center, International Medical Center of Japan, Tokyo, Japan Analysis of CYP2B6 genetic polymorphisms related to efavirenz concentrations in Japanese and Zambian. P-30 浜武　牧子国立感染症研究所エイズ研究センター Makiko Hamatake, AIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan Identification of hexa-peptidic motifs that inhibit the strand transfe activity of HIV-1 integrase pointing a molecular surface which serves as a potent drug target P-31 天野　将之熊本大学大学院医学薬学研究部血液内科学分野 Masayuki Amano, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan A novel bis-tetrahydrofranylurethane-containing nonpeptidic protease inhibitor (PI) GRL-98065 potent against multi-PI-resistant HIV in vitro P-32 こう　康博熊本大学大学院医学薬学研究部血液内科学分野 Yasuhiro Koh, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan Potent inhibition of HIV-1 replication by novel non-peptidyl small molecule inhibitors of protease dimerization P-33 近藤　孝昭熊本大学エイズ学研究センターウイルス制御分野 Takaaki Kondo, Center for AIDS Research, Kumamoto University, Kumamoto, Japan Unique cytokine secretion in human memory CD8+ T cells expressing chemokine receptor CCR4 P-34 高田　比呂志熊本大学エイズ学研究センターウイルス制御分野 Hiroshi Takata, Center for AIDS Research, Kumamoto University, Kumamoto, Japan The functional analysis of subsets in human effector CD8+ T cells P-35 松木　郁親　熊本大学エイズ学研究センターウイルス制御分野 Fumichika Matsuki, Center for AIDS Research, Kumamoto University, Kumamoto, Japan Identification of human Th17 cells by using multi-color flowcytric analysis P-36 岩永　寿真子熊本大学エイズ学研究センター予防開発分野 Sumako Iwanagai, Center for AIDS Research, Kumamoto University, Kumamoto, Japan Proliferation and Differentiation of Human B Cell in NOD/Scid/Jak-3 deficient Mice P-37 オマール・ディスキ熊本大学エイズ学研究センター予防開発分野 Omar Dessouki, Center for AIDS Research, Kumamoto University, Kumamoto, Japan Characterization of a minor human NK cell sub-population, CD56dimCD16- cells P-38 前田　洋助熊本大学大学院医学薬学研究部感染防御学 Yosuke Maeda, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan Characterization of human T cell lines resistant to HIV-1

エイズセミナーTOP		← 13 Sep.　　　　　　　　　　　　　　　　　　　　　　　　→ 14 Sep.