第８回熊本エイズセミナープログラムSession I Antiretroviral drugs
Yasuhiro Koh （Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan）
Potent inhibition of HIV-1 replication by novel non-peptidyl small molecule inhibitors of protease dimerization
Hirokazu Tamamura （Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo, Japan）
Development of anti-HIV agents based on chemokine receptor CXCR4 antagonists
Wataru Sugiura (National Institute of Infectious Diseases, Tokyo, Japan)
Genetic and structural interferences between protease inhibitor resistant mutations and Gag polymorphisms---their consequence in drug resistance selection and acquisition---
Ladislau C. Kovari (Wayne State University School of Medicne, Detroit, USA)
Structure-function studies of HIV-1 protease drug resistance
Junji Shibata (Center for AIDS Research, Kumamoto University, Kumamoto, Japan)
The single mutation in V2 domain affects quaternary structure of trimer gp120 and dramatically increases the sensitivity of primary human immunodeficiency virus type 1 isolates to neutralizing antibodies
Takamasa Ueno (Center for AIDS Research, Kumamoto University, Kumamoto, Japan)
CTL-mediated selective pressure influences dynamic evolution and pathogenic functions of HIV-1 Nef
Marcus Altfeld (Harvard Medical School, Boston, USA)
HIV-1-specific CD8+ T cell responses in Acute HIV-1 Infection
Poster Session II
11:10-12:00
Lunch(on your own)
12:00-12:50
12:50-14:10
Chair: Masafumi Takiguchi and Hiroyuki Gatanaga
12:50-13:05 Yuka Kawashima (Center for AIDS research, Kumamoto University, Kumamoto, Japan)
Control of HIV-1 replication by HIV-1-specific CTL in HLA-B*51+ long-term non progressors
13:05-13:30 Yasuko Tsunetsugu-Yokota (National Institute of Infectious Diseases, Tokyo, Japan)
Immune control of HIV-1 by restoring HIV-specific CD4+ T-cell function: a vaccine strategy against chronic HIV/SIV infection
13:30-14:10 Tomas Hanke (University of Oxford, Oxford, U.K)
Development of HIV-1 vaccines inducing protective T cell responses
14:25-16:00
Chair: Atsushi Koito and Tatsuyoshi Kawamura
14:25-14:50 Tatsuyoshi Kawamura (Faculty of medicine, University of Yamanashi, Yamanashi, Japan)
TLR2 activation augments HIV replication in Langerhans cells; implications for sexual transmission of HIV
14:50-15:15 Akifumi Takaori (Graduate School of Medicine, Kyoto University, Kyoto, Japan)
Escape of retroviruses from antiviral host defense by APOBEC3
15:15-15:40 Jun-ichi Sakuragi (Research Institute for Microbial Diseases, Osaka University, Osaka, Japan)
HIV-1 genome RNA dimerization and its roles on viral replication
15:40-16:00 Shinya Suzu (Center for AIDS Research, Kumamoto University, Kumamoto, Japan)
Spatial regulation of macrophage-specific tyrosine kinases Hck and M-CSF receptor by HIV-1 Nef