ACHIEVEMENTS

研究実績

発表論⽂

2022年

  • Md Belal Hossain, Tomoko Kobayashi, Sakurako Makimoto, Misaki Matsuo, Kohei Nishikaku, Benjy Jek Yang Tan, Akhinur Rahman, Samiul Alam Rajib, Kenji Sugata, Nagaki Ohnuki, Masumichi Saito, Toshiaki Inenaga, Kazuhiko Imakawa, Yorifumi Satou. Clone Dynamics and Its Application for the Diagnosis of Enzootic Bovine Leukosis. Journal of Virology. doi:https://doi.org/10.1128/jvi.01542-22
  • Benjy J. Y. Tan, Kenji Sugata, Masahiro Ono and Yorifumi Satou. HTLV-1 persistence and leukemogenesis: A game of hide-and-seek with the host immune system. Frontiers in Immunology. 13:991928. doi: 10.3389/fimmu.2022.991928
  • Tan B, Ono M, Satou Y. Single-cell transcriptome analysis of Treg, In: Ono M. (eds) Regulatory T Cells. pp259-278.
  • Victoria Maksimova, Susan Smith, Jaideep Seth, Cameron Phelps, Stefan Niewiesk, Yorifumi Satou, Patrick L Green, Amanda R Panfil. Identification and characterization of a novel enhancer in the HTLV-1 proviral genome. Frontiers in Immunology. 13:954077. doi: 10.3389/fimmu.2022.954077
  • Matsuo M, Ueno T, Monde K, Sugata K, Tan B, Rahman A, Miyazato P, Uchiyama K, Islam S, Katsuya H, Nakajima S, Tokunaga M, Nosaka K, Hata H, Utsunomiya A, Fujisawa,  Satou Y. Identification and characterization of a novel enhancer in the HTLV-1 proviral genome. Nature Communications. 13,2405, 2022. doi:10.1038/s41467-022-30029-9
  • Monde K, Satou Y, Goto M, Uchiyama Y, Ito J, Kaitsuka T, Terasawa H, Monde N, Yamaga S, Matsusako T, Wei FY, Inoue I, Tomizawa K, Ono A, Era T, Sawa T, Maeda Y. Movements of Ancient Human Endogenous Retroviruses Detected in SOX2-Expressing Cells., J Virol. in press
  • Rajib SA, Ogi Y, Hossain MB, Tanaka E, Kawaguchi T, Satou Y. A SARS-CoV-2 Delta variant containing mutation in the probe binding region used for qRT-PCR test in Japan exhibited atypical PCR amplification and might induce false negative result. Journal of Infection and Chemotherapy 28(5):669-677, 2022.
  • Katsuya H, Cook L, Rowan AG, Melamed A, Turpin J, Ito J, Islam S, Miyazato P, Tan B, Matsuo M, Miyakawa T, Nakata H, Matsushita S, Taylor GP, Bangham CRM, Kimura S, Satou Y. Clonality of HIV-1 and HTLV-1 infected cells in naturally coinfected individuals. The Journal of Infectious Diseases 225(2), 317-326, 2022.

2021年

  • Tan B, Sugata K, Reda O, Matsuo M, Uchiyama K, Miyazato P, Hahaut V, Yamagishi M, Uchimaru K, Suzuki Y, Ueno T, Suzushima H, Katsuya H, Tokunaga M, Uchiyama Y, Nakamura H, Sueoka E, Utsunomiya A, Ono M, Satou Y. HTLV-1 infection promotes excessive T cell activation and transformation into adult T cell leukemia/lymphoma. The Journal of Clinical Investigation 131(24), e150472, 2021.
  • Matsuda K, Islam S, Takada T, Tsuchiya K, Tan B, Hattori S, Katsuya H, Kitagawa K, Kim K,Matsuo M, Sugata K, Delino N, Gatanaga H, Yoshimura K, Matsushita S, Mitsuya H, Iwami S, Satou Y, Maeda K. A widely distributed HIV-1 provirus elimination assay to evaluate latency-reversing agents in vitro. Cell Reports Methods 1(8), 100122, 2021.
  • Hiyoshi M, Takahashi N, Eltalkhawy YM, Noyori O, Lotfi S, Panaampon J, Okada S, Tanaka Y, Ueno T, Fujisawa JI, Sato Y, Suzuki T, Hasegawa H, Tokunaga M, Satou Y, Yasunaga JI, Matsuoka M, Utsunomiya A, Suzu S. M-Sec induced by HTLV-1 mediates an efficient viral transmission. PLoS Pathogens 17:e1010126, 2021.
  • Ohnuki N, Kobayashi T, Matsuo M, Nishikaku K, Kusama K, Torii Y, Inagaki Y, Hori M, Imakawa K, Satou Y. A target enrichment high throughput sequencing system for characterization of BLV whole genome sequence, integration sites, clonality and host SNP. Scientific Reports 11(1), 4521, 2021.
  • Sugata K,Matsunaga Y, Yamashita Y, Nakatsugawa M, Guo T, Halabelian L, Ohashi Y, Saso K, Rahman M, Anczurowski M, Wang C, Murata K, Saijo H, Kagoya Y, Ly D, Burt B, Butler M, Mak T, Hirano N. Affinity-matured HLA class II dimers for robust staining of antigen-specific CD4+ T cells. Nature Biotechnology doi: 10.1038/s41587-021-00836-4, 2021.

2020年

  • Kalfaoglu B, Almeida-Santos J, Tye CA, Satou Y, Ono M. T-cell dysregulation in COVID-19. Biochemical and Biophysical Research Communications, 538:204-210, doi: 10.1016/j.bbrc.2020.10.079, 2020.
  • Tai-Nagara I, Hasumi Y, Kusumoto D, Hasumi H, Okabe K, Ando T, Matsuzaki F, Itoh F, Saya H, Liu C, Mukouyama Y, Linehan W, Liu X, Hirashima M, Suzuki Y, Funasaki S, Satou Y, Furuya M, Baba M, and Kubota Y. Blood and lymphatic systems are segregated by the FLCN tumor suppressor. Nature Communications, 11:6314, 11(1):6314, doi: 10.1038/s41467-020-20156-6, 2020.
  • Kalfaoglu B, Almeida-Santos J, Tye A C, Satou Y, Ono M. T-Cell Hyperactivation and Paralysis in Severe COVID-19 Infection Revealed by Single-Cell Analysis. Frontiers in Immunology, 11:589380, doi: 10.3389/fimmu.2020.589380. eCollection 2020, 2020.
    ＊国立研究開発法人日本医療研究開発機構（AMED） プレスリリース
    ＊国立大学法人熊本大学 プレスリリース
  • Aso H, Nagaoka S, Kawakami E, Ito J, Misawa N, Islam S, Tan B, Nakaoka S, Ashizaki K, Shiroguchi K, Suzuki Y, Satou Y, Koyanagi Y, Sato K. Multi-omics investigation revealing comprehensive characteristics of HIV-1-infected cells in vivo. Cell Reports, 32(2):107887, doi: 10.1016/j.celrep.2020.107887, 2020.
過去の発表実績