ヒトT細胞白血病ウイルスに関する網羅的かつ高精度な新規ウイルス配列情報解析方法を確立(佐藤研がCell Rep誌に発表)

Katsuya, H., Islam, S., Tan, B., Ito, J., Miyazato, P., Matsuo, M., Inada, Y., Iwase, S., Uchiyama, Y., Hata, H., Sato, T., Yagishita, N., Araya, N., Ueno, T., Nosaka, K., Tokunaga, M., Yamagishi, M., Watanabe, T., Uchimaru, K., Fujisawa, J., Utsunomiya, A., Yamano, Y. and Satou, Y.   The Nature of the HTLV-1 Provirus in Naturally Infected Individuals Analyzed by the Viral DNA-Capture-Seq Approach. Cell Reports, 29(3), pp.724-735.e4. ,  2019  (Division of Genomics and Transcriptomics)

DNAプローブと次世代シークエンスによる網羅的HIV-1プロウイルス解析法を確立(佐藤研がSci Rep誌に発表)

Iwase SC, Miyazato P, Katsuya H, Islam S, Tan B, Ito J, Matsuo M, Takeuchi H, Ishida T, Matsuda K, Maeda K, and Satou Y. HIV-1 DNA-capture-seq is a useful tool for the comprehensive characterization of HIV-1 provirus. Sci Rep, 9(1):12326, 2019   (Division of Genomics and Transcriptomics)

びまん性大細胞B細胞性リンパ腫におけるIL-34の異所性発現を発見(鈴研がClin Transl Immunology誌に発表)

Noyori O, Komohara Y, Nasser H, Hiyoshi M, Ma C, Pan C, Carreras J, Nakamura N, Sato A, Ando K, Okuno Y, Nosaka K, Matsuoka M, Suzu S. Expression of IL-34 correlates with macrophage infiltration and prognosis of diffuse large B-cell lymphoma. Clinical & Translational Immunology 8 (8): e1074, 2019.   (Division of Infection and Hematopoiesis)

タンザニアにおける治療前HIV感染者に認める薬剤耐性を発見(上野研がJ Antimicrob Chemother誌に発表)

G Barabona, M Mahiti, S Masoud, P Mbelele, A Shaban Mgunya, L Minja, B Sunguya, U Shigemi, M Matsuda, A Hachiya, Y Iwatani, E Lyamuya, T Ueno.  Pre-treatment and acquired HIV drug resistance in Dar es Salaam, Tanzania in the era of tenofovir and routine viral load monitoring. J Antimicrob Chemother https://doi.org/10.1093/jac/dkz272 , 2019  (Division of Infection and Immunity)

HLA-C*12:02を持つ感染者において免疫学的に重要なウイルスエピトープを特定(滝口研がJ. Virol誌に発表)

Takayuki Chikata, Wayne Paes, Tomohiro Akahoshi, Thomas Partridge, Hayato Murakoshi, Hiroyuki Gatanaga, Nicola Ternette, Shinichi Oka, Persephone Borrow, and Masafumi Takiguchi, Identification of immunodominant HIV-1 epitopes presented by HLA-C*12:02, a protective allele, using an immunopeptidomics approach, J. Virol, 93(17), e00634-19,2019   (Division of International Collaboration Research / Takiguchi Lab.)

publicationsを更新しました。

Ueno M, Nogawa M, Siddiqui R, Watashi K, Wakita T, Kato N, Ikeda M, Okimura T, Isaka S, Oda T, Ariumi Y. Acidic polysaccharides isolated from marine algae inhibit the early step of viral infection. Int. J. Biol. Macromol. 124:282-290, 2019.(Division of Retroelement)


Smita Kulkarni, Alexandra Lied, Viraj Kulkarni, Marijana Rucevic, Maureen P. Martin, Victoria Walker-Sperling, Stephen K. Anderson, Rodger Ewy, Sukhvinder Singh, Hoang Nguyen, Paul J. McLaren, Mathias Viard, Vivek Naranbhai, Chengcheng Zou, Zhansong Lin, Hiroyuki Gatanaga, Shinichi Oka, Masafumi Takiguchi, Chloe L. Thio, Joseph Margolick, Gregory D. Kirk, James J. Goedert, W. Keith Hoots, Steven G. Deeks, David W. Haas, Nelson Michael, Bruce Walker, Sylvie Le Gall, Fatema Z. Chowdhury, Xu G. Yu and Mary Carrington, CCR5AS lncRNA variation differentially regulates CCR5, influencing HIV disease outcome, Nat Immunol. 20:824-834, 2019(Division of International Collaboration Research / Takiguchi Lab)


Nozomi Kuse, Xiaoming Sun, Tomohiro Akahoshi, Anna Lissina, Takuya Yamamoto, Victor Appay, and Masafumi Takiguchi, Priming of HIV-1-specific CD8+ T cells with strong functional properties from naive T cells, EBioMedicine 42:109-119, 2019(Division of International Collaboration Research / Takiguchi Lab)


Chengcheng Zou*, Hayato Murakoshi*, Nozomi Kuse, Tomohiro Akahoshi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, Tomas Hanke, and Masafumi Takiguchi (*Equal contribution), Effective suppression of HIV-1 replication by CTLs specific for Pol epitopes in conserved mosaic vaccine immunogens, J. Virol. 93:e02142-18, 2019(Division of International Collaboration Research / Takiguchi Lab)

ヒトレトロウイルス学共同研究センター
ヒトレトロウイルス学共同研究センター 鹿児島大学キャンパス
熊本大学キャンパス
生命化学研究部・教育部
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ヒトレトロウイルス学共同研究センター 熊本キャンパス

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