M-Sec promotes the production of infectious HIV-1 virus through the exocyst complex in macrophagesをPLoS Pathogensに発表しました!(鈴研,PLoS Pathogens)

Mahmoud RM, Hiyoshi M, Abdelnaser RA, Monde K, Monde N, Koma T, Mizuno H, Habash SA, Takahashi N, Maeda Y, Ono A, Suzu S.

PLoS Pathog. 2026 Jun 1;22(6):e1013717. doi: 10.1371/journal.ppat.1013717.

M-Sec promotes the production of infectious HIV-1 virus through the exocyst complex in macrophages

 

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Position-5-driven reorientation of an immunodominant HLA-A*24:02 SARS-CoV-2 epitope drives universal T cell escapeをJCI Insightに発表しました! (本園研、JCI Insight)

Nakama T#, Wall A#, Dolton G#, Tan LR, Thomas H, Hamana H, Aritsu Y, Tan TS, Toyoda M, Goto Y, Li H, Kitamatsu M, Udaka K, Miyashita Y, Oshiumi H, Nakamura K, Nagasaki Y, Minami R, Nakata H, Rizkallah PJ, Kishi H, Ueno T, Sewell AK*, Motozono C*

Position-5-driven reorientation of an immunodominant HLA-A*24:02 SARS-CoV-2 epitope drives universal T cell escape

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N-terminal pyroglutamylation of an HLA-A24-restricted immunodominant epitope enhances SARS-CoV-2-specific T cell responsesをFrontiers in Immunologyに発表しました! (本園研、Frontiers in Immunology)

Aritsu Y, Kitabatake M, Kurose A, Hamana H, Nakama T, Yamada K, Furukawa R, Ouji-Sageshima N, Hara A, Yasuike K, Itami S, Li H, Udaka K, Kishi H, Ueno T, Nakagawa S, Ito T, Kawashita N, Kitamatsu M and Motozono C

N-terminal pyroglutamylation of an HLA-A24-restricted immunodominant epitope enhances SARS-CoV-2-specific T cell responses

DOI : 10.3389/fimmu.2026.1758642

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Human peritoneal CCR2LowCRIgHigh macrophage subset exhibits embryonic origin-like phenotypesをHuman Cellに発表しました(鈴研、Human Cell)

Takahashi N, Habash SA, Komohara Y, Usuki S, Yasunaga KI, Hino S, Abdelnaser RA, Einarsdottir T, Nomura T, Yonemura A, Ishimoto T, Suzu S.

Human peritoneal CCR2LowCRIgHigh macrophage subset exhibits embryonic origin-like phenotypes

Human Cell

doi: 10.1007/s13577-026-01379-z.

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The Differentially Regulated Cousins: Insights into the Differences in Transcriptional Regulatory Mechanisms Between HTLV-1 and HIV-1 Viruses. をVIRUSESに発表しました!(佐藤研、VIRUSES)

Reda O, Satou Y.

The Differentially Regulated Cousins: Insights into the Differences in Transcriptional Regulatory Mechanisms Between HTLV-1 and HIV-1
Viruses.

VIRUSES

DOI:  10.3390/v18010140.

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Dynamics of lung-infiltrating virus-specific T cells associated with age-dependent SARS-CoV-2 pneumonia severityをPLOS.Pathogensに発表しました!(野村研、PLOS.Pathogens)

Kurokawa R, Mtali CS, Daniel IJ, Einarsdottir T, Reda O, Irie N, Sakhor W, Niimura K, Takatori M, Sugata K, Tye CA, Satou Y, Ono M, Nomura T

Dynamics of lung-infiltrating virus-specific T cells associated with age-dependent SARS-CoV-2 pneumonia severity

PLOS.Pathogens

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CD8+T 細胞とKIR2DL2+NK細胞によるHIV-1の逃避ウイルスの選択と増殖抑制に関する分子レベルでの研究論文をNature Communications誌に発表しました (滝口研、Nat Commun 16: 9796, 2025)

Takayuki Chikata*, Kimiko Kuroki*, Nozomi Kuse*, Anna E Kliszczak, Wayne Paes, Nanami Tomioka, Robert Parker, Aure Aflalo, Tomohiro Akahoshi, Yu Zhang, Ryoya Yamashita, Ryuma Sakata, Hiroki Kusaka, Yosuke Watanabe, Annalisa Nicastri, Haruki Matsubara, Toyoyuki Ose, Shunsuke Kita, Shinichi Oka, Hiroyuki Gatanaga, Zhansong Lin, Nicola Ternette, Persephone Borrow, Katsumi Maenaka,, Masafumi Takiguchi, (*equal contribution), Molecular basis for selection and inhibition of HIV-1 escape virus by T cells and KIR2DL2+NK cells. Nat Commun. 16: 9796, 2025

詳しくはこちら

TNFAIP2 increases macrophage response to CSF-1 through multiple effects on CSF-1 receptorをJournal of Leukocyte Biologyに発表しました(鈴研、Journal of Leukocyte Biology)

Abdelnaser RA, Hiyoshi M, Takahashi N, Kimura S, Hase K, Ohno H, Monde K, Ono A, Suzu S.

TNFAIP2 increases macrophage response to CSF-1 through multiple effects on CSF-1 receptor

Journal of Leukocyte Biology

doi: 10.1093/jleuko/qiaf151.

HIV-1-exposed seronegative individualsにおけるHIV-1特異的CD8+T細胞の解析に関する論文をPNAS Nexus誌に発表しました(滝口研、PNAS Nexus 4: pgaf336, 2025)

Hung The Nguyen*, Takayuki Chikata*, Nozomi Kuse, Yu Zhang, Diep Thi Ngoc Pham, Nga Thi Do, Thanh Cong Nguyen, Ngoc Bich Lung, Hao Thi Minh Bui, Hiroyuki Gatanaga, Giang Van Tran, Binh Thanh Nguyen, Do Van Nguyen, Le Minh Giang, Shinichi Oka, and Masafumi Takiguchi (*equal contribution), HIV-1-specific CD8+ T cells with different abilities to recognize HIV-1-infected cells in HIV-1-exposed seronegative individuals. PNAS Nexus 4: pgaf336, 2025

→詳しくはこちら

Molecular basis of potent antiviral HLA-C-restricted CD8+ T cell response to an immunodominant SARS-CoV-2 nucleocapsid epitopeをNature Communicationsに発表しました!(上野研、Nature Communications)

Yoshihiko Goto, You Min Ahn, Mako Toyoda, Hiroshi Hamana, Yan Jin, Yoshiki Aritsu, Takeshi Nakama, Yuka Tajima, Janesha C. Maddumage, Huanyu Li, Mizuki Kitamatsu, Hiroyuki Kishi, Akiko Yonekawa, Dhilshan Jayasinghe, Nobuyuki Shimono, Yoji Nagasaki, Rumi Minami, Takashi Toya, Noritaka Sekiya, Yusuke Tomita, Demetra S. M. Chatzileontiadou, Hirotomo Nakata, So Nakagawa, Takuro Sakagami, …Chihiro Motozono

Molecular basis of potent antiviral HLA-C-restricted CD8+ T cell response to an immunodominant SARS-CoV-2 nucleocapsid epitope

Nature Communications

日本人COVID-19感染回復者で誘導され、長期間維持される強力なキラーT細胞応答を発見

日本人COVID-19感染回復者で誘導され、長期間維持される強力なキラーT細胞応答を発見 | 熊本大学

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